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Effects of catecholamines, nicotine, acetylcholine and potassium on the mechanical activity of the colonic muscularis mucosae in the cat

  • Second International Symposium On Gastrointestinal Motility
  • Published:
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Conclusions

Our conclusions on cat colonic muscularis mucosae can be summarized as follows: The smooth muscle containsα-excitatory andβ-inhibitory receptors. Both adrenergic and nonadrenergic inhibitory nervous structures, which can be excited through nicotinic and muscarinic receptors, are present. The possible role of 5-HT in permitting nonadrenergic inhibitory responses is suggested. In the colonic muscularis mucosae, the apparent lack of cholinergic motor neurones has been demonstrated.

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References

  1. Onori L, Greco V, Fabbrini A, et al.: Microscopic patterns of the colonic mucosal surface. Investigations in human subjects and experimental animals. Experientia 24: 1252, 1968

    Google Scholar 

  2. Bartlet AL, Hassan T: Some actions of histamine and 5-hydroxytryptamine on isolated chicken oesophagus. Brit J Pharmacol 32:156, 1968

    Google Scholar 

  3. Burn JH, Gibbons WR: The release of noradrenaline from sympathetic fibres in relation to calcium concentration. J Physiol 181:214, 1965

    Google Scholar 

  4. Falck B: Observation on the possibilities of the cellular localization of monoamines by a fluorescence method. Acta Physiol Scand 56:Suppl:197, 1962

    Google Scholar 

  5. King CE, Glass LC, Towsend SE: The circular component of the muscularis mucosae of the small intestine of the dog. Amer J Physiol 148:667, 1947

    Google Scholar 

  6. Walder DN: The muscularis mucosae of the human stomach. J Physiol 120:365, 1953

    Google Scholar 

  7. Ellis S, Rasmussen H: The atropine-fast nicotine stimulation of the rabbit's intestine and of the muscularis mucosae of the dog's intestine. J Pharmacol Exp Ther 103:259, 1951

    Google Scholar 

  8. Bianchi C, Beani L, Frigo GM, et al: Further evidence for the presence of non-adrenergic inhibitory structures in the guinea pig colon. Europ J Pharmacol 4:51, 1968

    Google Scholar 

  9. Filogamo G, Muti R: A propos d'une technique de dénervation du canal alimentaire au moyen du froid. Compt Rend Ass Anat 141:873, 1968

    Google Scholar 

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Authors and Affiliations

  1. From the Gastroenterology Unit, Second Medical Clinic of the University, Rome, Italy

    L. Onori MD, C. A. Friedmann MSc, G. M. Frigo MD & M. Tonini

  2. the Department of Pharmacology of the University of Pisa, Italy

    L. Onori MD, C. A. Friedmann MSc, G. M. Frigo MD & M. Tonini

Authors
  1. L. Onori MD
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  2. C. A. Friedmann MSc
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  3. G. M. Frigo MD
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  4. M. Tonini
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Supported by CNR Grant No. 115-123-1357.

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Onori, L., Friedmann, C.A., Frigo, G.M. et al. Effects of catecholamines, nicotine, acetylcholine and potassium on the mechanical activity of the colonic muscularis mucosae in the cat. Digest Dis Sci 16, 689–692 (1971). https://doi.org/10.1007/BF02239590

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  • DOI: https://doi.org/10.1007/BF02239590

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