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Pediatric Cardiology

, Volume 11, Issue 2, pp 113–116 | Cite as

Arrhythmogenic right ventricular dysplasia in brother and sister: Is it related to myocarditis?

  • Karl-Göran Sabel
  • Carina Blomström-Lundqvist
  • S. Bertil Olsson
  • Sverker Eneström
Case Reports

Summary

Two cases of arrhythmogenic right ventricular dysplasia (ARVD) in siblings are reported. In the boy, 14 years old, the clinical history, ECG, echocardiography, and histopathological findings were consistent with ARVD. Premature ventricular contractions of left bundle branch block (LBBB) pattern were recorded but no ventricular tachycardia (VT). A high titer against mycoplasma and increased concentrations of immunoglobulins were found. Two years after his first admission he died suddenly. Autopsy revealed severe right ventricular (RV) myocardial damage, with fat cell infiltration and collagenous tissue. His sister presented with sustained VT of LBBB pattern 2 years later, at 12 years of age. Vaccination against rubella and signs of upper respiratory illness had preceded the symptoms. During the following 9 days ECGs and serum enzymes indicated the development of left ventricular (LV) infarction. Echocardiography revealed an enlarged RV and a normal LV. After 6 weeks both RV and LV showed akinetic areas and sacculations. We suggest that myocarditis may be a precipitating factor in ARVD, and perhaps the prerequisite for its manifestation.

Key Words

Arrhythmogenic right ventricular dysplasia Dilated cardiomyopathy Myocarditis Familial occurrence 

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Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • Karl-Göran Sabel
    • 1
  • Carina Blomström-Lundqvist
    • 2
  • S. Bertil Olsson
    • 2
  • Sverker Eneström
    • 3
  1. 1.Section of Paediatric Cardiology, Department of PaediatricsEast HospitalGöteborg
  2. 2.Division of Cardiology, Med Department ISahlgrenska HospitalGöteborg
  3. 3.Department of PathologyUniversity HospitalLinköpingSweden

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