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Studies on the secretions from isolated duodenal loops

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Abstract

Volume and electrolyte composition were studied from the juice of isolated duodenal loops in 3 dogs. The mean volume rate of fasting basal secretion was 0.7 ml/30 min. A significant increase in volume (p < 0.05) and bicarbonate output (p < 0.05) was found in response to a 600-g meat meal. Bicarbonate concentration was not related to volume rate of secretion. The concentrations of sodium and bicarbonate were similar to those of blood plasma, whereas the concentrations of chloride and potassium were higher.

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References

  1. Cooke, A. R. “The Glands of Brunner.”Handbook of Physiology, Alimentary Canal (Vol. 2). American Physiological Society, Washington, DC, 1967, Chap. 61.

    Google Scholar 

  2. Pelot, D., andGrossman, M. I. Distribution and fate of pancreatic enzymes in small intestine of the rat.Amer J Physiol 202:285, 1962.

    PubMed  Google Scholar 

  3. Snedecor, G. W., andCochran, W. G. Statistical Methods (ed. 6). Iowa State Univ. Press, Ames, 1967.

    Google Scholar 

  4. Florey, H. W., andHarding, H. E. A humoral control of secretion of Brunner's glands.Proc Roy Soc [Biol] 117:68, 1935.

    Google Scholar 

  5. Sonnenschein, R. R., Grossman, M. I., andIvy, A. C. The humoral regulation of Brunner's glands.Acta Med Scand 196 (Suppl.):296, 1947.

    Google Scholar 

  6. Cooke, A. R., andGrossman, M. I. Studies on the secretion and motility of Brunner's gland pouches.Gastroenterology 51:506, 1966.

    PubMed  Google Scholar 

  7. Landor, J. H., Brasher, P. H., andDragstedt, L. R. Experimental studies on the secretions of the isolated duodenum.Arch Surg (Chicago) 71:727, 1955.

    Google Scholar 

  8. Blickenstaff, D., Grossman, M. I., andIvy, A. C. Stimulating effect of sugar, fat and meat meals on duodenal secretion in the dog.Amer J Physiol 158:122, 1949.

    Google Scholar 

  9. Hollander, F. The electrolyte pattern of gastric mucinous secretion: its implication for cystic fibrosis.Ann NY Acad Sci 106:757, 1963.

    PubMed  Google Scholar 

  10. Grossman, M. I. “The Secretion of the Pyloric Glands in the Dog. InSymposia and Special Lectures. XXI International Congress of Physiological Sciences, Buenos Aires, p. 226.

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Authors and Affiliations

  1. From the Veterans Administration Center, Los Angeles

    Allan R. Cooke MB (MRACP)

  2. Department of Medicine, UCLA Medical School, 90024, Los Angeles, Calif

    Allan R. Cooke MB (MRACP)

Authors
  1. Allan R. Cooke MB
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Additional information

Supported by Veterans Administration Research Fund and by Grant 08354 from the US Public Health Service

The author thanks John Alexander and Ray Lichter for technical assistance. This study was done in the laboratory of Dr. Morton I. Grossman to whom the author is indebted

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Cooke, A.R. Studies on the secretions from isolated duodenal loops. Digest Dis Sci 14, 394–399 (1969). https://doi.org/10.1007/BF02239359

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