Abstract
Ulcerative colitis confined to the rectum or rectum and sigmoid was studied in 234 patients. During a prolonged period of follow-up, these patients had an extremely benign clinical course when compared with that experienced with the diffuse disease. A minimum of morbidity and not a single death occurred. Only 10 patients required operation on the colon for control of disease. Extracolonic manifestations were virtually absent. No malignant degeneration occurred. Although we believe that this disease is part of the spectrum of ulcerative colitis, its anatomic confinement to the distal colon allows prediction of a much more benign clinical course.
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Nugent, F.W., Veidenheimer, M.C., Zuberi, S. et al. Clinical course of ulcerative proctosigmoiditis. Digest Dis Sci 15, 321–326 (1970). https://doi.org/10.1007/BF02239286
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DOI: https://doi.org/10.1007/BF02239286