The American Journal of Digestive Diseases

, Volume 17, Issue 1, pp 59–67 | Cite as

Acquired bisalbuminemia with hyperamylasemia

  • George G. Shashaty
  • M. A. Atamer
  • Miss Eleanor Shields
Original Articles


Two patients with pancreatitis and hyperamylasemia had an acquired double albumin on serum electrophoresis, with the anomalous albumin migrating more rapidly than the normal. The quantity of the rapidly migrating fraction appeared to be directly related to the serum amylase level. No immunologic differences were detectable between the two albumins. Several studies suggested that the elevated serum amylase level was not caused by macroamylasemia. Possible mechanisms for the production of double albumin include: amylase to albumin binding, an enzymatic change of albumin by amylase, or the presence in serum of other substances that alter the electric charge of albumin.


Public Health Albumin Pancreatitis Electrophoresis Amylase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1972

Authors and Affiliations

  • George G. Shashaty
    • 1
  • M. A. Atamer
    • 1
  • Miss Eleanor Shields
    • 1
  1. 1.From the Section of Hematology and Immunology, Division of MedicineGrasslands HospitalValhalla

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