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Journal of Neuro-Visceral Relations

, Volume 31, Issue 2, pp 171–188 | Cite as

Effect of stimulation and coagulation of the midbrain reticular formation on the bronchial musculature; a modification of histamine susceptibility

  • A. Przybylski
Article
  • 23 Downloads

Summary

The influence of the midbrain reticular formation on bronchial muscle tonus in the guinea pig was examined. In the midbrain reticular formation functionally interrelated regions were distinguished that play a role in the control of bronchial smooth muscle tonus. The dorso-caudal regions of the midbrain reticular formation activate the constriction of the bronchial tubes, whereas the ventro-rostral regions exert an antagonistic influence. The dorso-caudal regions act on the effector mainly by phasic regulation through the parasympathetic nervous system. The facilitation of the dilatatory reaction is connected with the prepotency of the sympathetic nervous system and an activation of the hypophysio-adrenal system.

Keywords

Smooth Muscle Histamine Sympathetic Nervous System Muscle Tonus Phasic Regulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Bei Meerschweinchen wurde die Einwirkung der Formatio reticularis des Hirnstammes auf den Tonus der Bronchialmuskulatur untersucht. In der Formatio reticularis wurden die funktionell zusammenhängenden Strukturen, welche den Tonus der Bronchialmuskulatur regulieren, lokalisiert. Die dorso-caudalen Gebiete der Formatio reticularis aktivieren die Verengerung der Atmungswege, die ventrorostralen Gebiete wirken antagonistisch auf die glatte Bronchialmuskulatur. Die dorso-caudalen Gebiete wirken über das parasympathische Nervensystem. Die Aktivierung der Entspannung hängt mit dem überwiegenden Einfluß des sympathischen Nervensystems zusammen und ist an die Aktivierung des hypophysäradrenalen Systems gebunden.

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Copyright information

© Springer-Verlag 1969

Authors and Affiliations

  • A. Przybylski
    • 1
  1. 1.Centre of Experimental and Clinical MedicinePolish Academy of SciencesWarsawPoland

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