Chemistry of Natural Compounds

, Volume 35, Issue 1, pp 80–81 | Cite as

Synthesis of (22E,24R)-5a-ergosta-2,7,22-trien-6-one

  • N. V. Kovganko
  • S. N. Sokolov


The synthesis of the 5a-hydroxy-2,7,22-trien-6-one (3) has been achieved by the mesylation of ergosterol (1a) and oxidation of the resulting mesylate (1b) with chronic acid to 3β,5a-dihydroxy-7,22-dien-6-one 3-mesylate, followed by elimination.


Organic Chemistry Ergosterol Chronic Acid 
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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • N. V. Kovganko
  • S. N. Sokolov

There are no affiliations available

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