Summary
The benzimidazole anthelmintic, oxfendazole, was used as an oral suspension at 4·5 and 2·8 mg/kg to treat naturally infested indigenous buffaloes in Egypt. Worms of the generaHaemonchus, Cooperia, Trichostrongylus, Ostertagia, Chabertia andOesophagostomum were identified in the animals prior to treatment. A 100% reduction in faecal egg counts was obtained at the 4·5 mg/kg level when compared to untreated control animals. Reductions in faecal egg counts greater than 90% were recorded at 2·8 mg/kg and these exceeded reductions obtained by drenching with the older benzimidazole anthelmintic, thiabendazole, at 67 and 111 mg/kg.
Résumé
L'oxfendazole, anthelminthique benzimidazolé, a été utilisé oralement en suspension à 4,5 et 2,8 mg/kg dans le traitement de buffles égyptiens naturellement parasités. Des vers du genreHaemonchus, Cooperia, Trichostrongylus, Ostertagia, Chabertia etOesophagostomum ont été identifiés chez les animaux avant leur traitement.
A 4,5 mg/kg une réduction de 100 p. 100 dans le décompte des oeufs contenus dans la matière fécale a été constatée pa rapport à ce qui a été observé chez des animaux non traités. Des réductions pouvant atteindre 90 p. 100 ont été obtenues avec la dose de 2,8 mg/kg, qui dépassent celles obtenues par administration d'un ancien anthelminthique de la série du benzimidazole, le thiabendazole à la dose de 67 et de 111 mg/kg.
Resumen
Se utilizó una suspensión oral del antihelmíntico benzimidazolico oxfendazole, en dosis de 4.5 y 2.8 mg/kg de peso, contra nemátodos gastrointestinales de bufalos infectados naturalmente. Antes del tratamiento, se identificaron parásitos del generoHaemonchus, Cooperia, Trichostrongylus, Ostertagia, Chabertia yOesophagostomun en los animales experimentales. Los resultados fueron ampliamente favorables (reducción del 100% en el contéo de huevos) con la dosis de 4.5 mg/kg, comparado con el control sin tratamiento. Con la dosis de 2.8 mg/kg de peso, se obtuvo una reducción del 90% en el contéo de huevos, excediendo esta la obtenida con el thiabendazole y el anterior antihelmíntico benzimidazole en dosis de 111 y 67 mg/kg de peso respectivamente.
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Michael, S.A., El Refaii, A.H. & Higgins, A.J. Efficacy of oxfendazole against naturally acquired gastro-intestinal nematode infestations in buffaloes in Egypt. Trop Anim Health Prod 11, 159–163 (1979). https://doi.org/10.1007/BF02237793
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DOI: https://doi.org/10.1007/BF02237793