Diseases of the Colon & Rectum

, Volume 43, Issue 4, pp 548–550 | Cite as

Radical excision of multifocal anal intraepithelial neoplasia

Report of a case
  • D. J. Browse
  • R. J. Baigrie
  • P. A. Goldberg
  • J. Nevin
Case Reports


PURPOSE: The aim of this study was to describe the technique of radical excision of multifocal anal intraepithelial neoplasia and discuss controversial issues surrounding the management of this condition. METHOD: We describe the case of a 31-year-old female with previous vulval warts, vulval squamous carcinoma, and recent immunosuppression who had widespread anal intraepithelial neoplasia excised, and the resulting defect was split-skin grafted, including the anal canal. RESULTS: Excision and split-skin grafting was successful in removing the disease and left a satisfactory cosmetic and functional result. CONCLUSION: Diffuse, high-grade, anal intraepithelial neoplasia is rare. Excision of these lesions remains controversial but may be the best option.

Key words

Anal neoplasms Anal intraepithelial neoplasia Anal carcinoma Anal dysplasia Vulval intraepithelial neoplasia 


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Copyright information

© American Society of Colon and Rectal Surgeons 2000

Authors and Affiliations

  • D. J. Browse
    • 1
  • R. J. Baigrie
    • 1
  • P. A. Goldberg
    • 1
  • J. Nevin
    • 2
  1. 1.From the Department of SurgeryGroote Schuur Hospital and the University of Cape TownCape TownSouth Africa
  2. 2.Department of GynaecologyGroote Schuur Hospital and the University of Cape TownCape TownSouth Africa

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