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Radiation-induced total regression of a highly recurrent giant perianal condyloma

Report of a case


We report a case of a highly recurrent giant perianal condyloma, or Buschke-Lowenstein tumor, which was successfully treated by telecobalt therapy. We conclude that radiation therapy is an optional treatment modality for the management of giant perianal condylomata in selected cases.

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  1. 1.

    Surrel JÁ, Mackeigan JM. Anal perianal warts. Curr Ther Colon Rectal Surg 1990;1:49–52.

    Google Scholar 

  2. 2.

    Leads From the MMWR. Condyloma Acuminatum—United States, 1966–1981. JAMA 1983;1966:250:336–9.

    Google Scholar 

  3. 3.

    Andrews HÁ, Wyke J, Rat T,et al. Sexually transmitted disease: a new hazard for the gastroenterologist? Gut 1986;27:A1259–1261.

    Google Scholar 

  4. 4.

    Koutsky LA, Galloway DA, Holmes KK. Epidemiology of genital human papillomavirus infection. Epidemiol Rev 1988;10:122–63.

    Google Scholar 

  5. 5.

    Buschke A, Loewenstein L. Über carcinomahnliche condylomata des penis. Klin Wochenschr 1925;4:1726–7.

    Google Scholar 

  6. 6.

    Elliot MS, Werner ID, Immelman EJ, Harrison AC. Giant condyloma (Buschke-Löwenstein tumor) of the anorectum. Dis Colon Rectum 1979;22:497–500.

    Google Scholar 

  7. 7.

    Swerdlow DB, Salvati EP. Condyloma acuminatum. Dis Colon Rectum 1971;14:226–31.

    Google Scholar 

  8. 8.

    Edstron S, Johannson S, Lindstron J. Verrucous squamous cell carcinoma of the larynx: evidence for increased metastatic potential after irradiation. Otolaryngol Head Neck Surg 1987;97:381–4.

    Google Scholar 

  9. 9.

    Schawde JG, Wara WM, Dedo HH, Philip TL. Radiotherapy for verrucous carcinoma. Radiology 1976;120:677–9.

    Google Scholar 

  10. 10.

    Nigro ND, Vaitkevicius VK, Considine BJ. Combined therapy for cancer of the anal canal: a preliminary report. Dis Colon Rectum 1974;17:354–6.

    Google Scholar 

  11. 11.

    Sillamniku B, Bauer W, Painter C. Clinical and histopathological considerations for the diagnosis and treatment of verrucous carcinoma of the larynx. Arch Otorhinolaryngol 1989;246:126–32.

    Google Scholar 

  12. 12.

    Butler TW, Gefer J, Kleto D, Schuck EH III, Ruffner BW. Squamous-cell carcinoma of the anus in condyloma acuminatum: successful treatment with preoperative chemotherapy and radiation. Dis Colon Rectum 1987;30:293–5.

    Google Scholar 

  13. 13.

    Habr-Gama A, da Silva e Sousa AH Jr, Nadalin W, Gansl R, da Silva JH, Pinotti HW. Epidermoid carcinoma of the anal canal: results of treatment by combined chemotherapy and radiation therapy. Dis Colon Rectum 1989;32:773–7.

    Google Scholar 

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Correspondence to Carlos Walter Sobrado M.D..

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Sobrado, C.W., Mester, M., Nadalin, W. et al. Radiation-induced total regression of a highly recurrent giant perianal condyloma. Dis Colon Rectum 43, 257–260 (2000).

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Key words

  • Radiation
  • Regression
  • Condyloma acuminatum
  • Buschke-Löwenstein tumor