Abstract
To our knowledge, there has been no report of the use of indigo carmine dye spraying for the diagnosis of intraepithelial neoplasia. An asymptomatic 58-year-old female was referred to our hospital with a diagnosis of squamous-cell carcinoma in the anal canal. After indigo carmine dye spraying the margin and surface appearance of the lesion could be clearly defined. The lesion was completely removed by transanal resection. Final histologic diagnosis was squamous-cell carcinomain situ with koilocytosis. Our case suggests that indigo carmine could be useful for the diagnosis of intraepithelia neoplasia.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Yoshikawa H, Kawana T, Kitagawa K, Mizuno M, Yoshikura H, Iwamoto A. Detection and typing of multiple genital human papillomaviruses by DNA amplification with consensus primers. Jpn J Cancer Res 1991;82:524–31.
Cleary RK, Schaldenbrand JD, Fowler JJ, Schuler JM, Lampman RM. Perianal Bowen's disease and anal intraepithelial neoplasia: review of the literature. Dis Colon Rectum 1999;42:945–51.
Scholefield JH, Sonnex C, Talbot IC,et al. Anal and cervical intraepithelial neoplasia: possible parallel. Lancet 1989;2:765–9.
Surawicz CM, Critchlow C, Sayer J,et al. High grade anal dysplasia in visually normal mucosa in homosexual men: seven cases. Am J Gastroenterol 1995;90:1776–8.
Shim CS. Staining in gastrointestinal endoscopy: clinical application and limitations. Endoscopy 1999;31:487–96.
Author information
Authors and Affiliations
Additional information
Supported by the second-term Comprehensive 10-Year Strategy for Cancer Control of the Health and Welfare Ministry of Japan.
About this article
Cite this article
Yamaguchi, T., Moriya, Y., Fujii, T. et al. Anal canal squamous-cell carcinomain situ, clearly demonstrated by indigo carmine dye spraying. Dis Colon Rectum 43, 1161–1163 (2000). https://doi.org/10.1007/BF02236566
Issue Date:
DOI: https://doi.org/10.1007/BF02236566