The American Journal of Digestive Diseases

, Volume 12, Issue 9, pp 853–861 | Cite as

Intravenous galactose tolerance test with the use of an enzymatic method for the determination of galactose

  • Bertil Tengström
  • Magnus Hjelm
  • Carl-Henric de Verdier
  • Ivar Werner


A galactose-tolerance test is presented that is a modification of the method of Colcheret al.16 Galactose is administered by a single rapid intravenous injection or infusion (350 mg./kg. body weight). The galactose values during 60–80 min. after the administration are determined in capillary blood and form an approximately straight line in a semilogarithmic system. The result is expressed as the τ1/2 values for galactose.

The galactose determinations are made with a galactose oxidase method. The test is simple to perform, and the results are reproducible.

The test was carried out on a clinical series, and was found to give valuable quantitative information about liver function and to aid in the distinction between parenchymatous and obstructive jaundice.


Public Health Body Weight Liver Function Galactose Intravenous Injection 
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Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1967

Authors and Affiliations

  • Bertil Tengström
    • 1
  • Magnus Hjelm
    • 1
  • Carl-Henric de Verdier
    • 1
  • Ivar Werner
    • 1
  1. 1.From the Departments of Internal Medicine and Clinical ChemistryUniversity HospitalUppsalaSweden

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