Advertisement

Chemistry of Natural Compounds

, Volume 36, Issue 2, pp 152–155 | Cite as

Synthesis and crystal structure of a pyrazole derivative of artemisia ketone

  • G. A. Atazhanova
  • A. T. Kulyyasov
  • A. D. Dembitskii
  • V. A. Raldugin
  • M. M. Shakirov
  • I. Yu. Bagryanskaya
  • Yu. V. Gatilov
  • S. M. Adekenov
  • G. A. Tolstikov
Article
  • 122 Downloads

Abstract

The oxime of artemisia ketone is smoothly converted to the pyrazole derivative by sodium nitrite and acetic acid in CHCl3. The structure of the pyrazole was found by x-ray structural analysis. The PMR and13C NMR spectra were interpreted using two-dimensional1H−13C NMR (COSY, COLOC).

Key words

Artemisia glabella artemisia ketone 5-(1′,1′-dimethylallyl)-3,3-dimethyl-3H-pyrazole-N,N′-dioxide synthesis 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    K. Takemoto and T. Nakajima,Yakugaku Zasshi,77, 1307 (1957);Chem. Abstr.,52, 4478 (1958).Google Scholar
  2. 2.
    L. H. Zalkow, D. R. Brannon, and J. W. Uecke,J. Org. Chem.,29, 2786 (1964).Google Scholar
  3. 3.
    G. A. Atazhanova, A. D. Dembitskii, N. I. Zhizhin, and S. M. Adekenov,Khim. Prir. Soedin., 193 (1999).Google Scholar
  4. 4.
    G. A. Atazhanova, Author's Abstract of a Candidate Dissertation in Chemical Sciences, Karaganda (1999).Google Scholar
  5. 5.
    M. I. Goryaev, T. E. Serkebaeva, G. I. Krotova, and A. D. Dembitskii,Rast. Resur.,3, 63 (1967).Google Scholar
  6. 6.
    Yu. V. Gatilov, L. V. Basalaeva, N. K. Kozlov, M. M. Shakirov, and V. A. Raldugin,Khim. Prir. Soedin., 704 (1995).Google Scholar
  7. 7.
    J. P. Freeman,J. Org. Chem.,27, 1309 (1962).Google Scholar
  8. 8.
    F. H. Allen, O. Kennard, D. G. Watson, L. Brammer, A. G. Orpen, and R. Taylor,J. Chem. Soc., Perkin Trans. II, No. 12, 1 (1987).Google Scholar
  9. 9.
    F. H. Allen and O. Kennard,Chem. Des. Automat. News,8, 131 (1993).Google Scholar
  10. 10.
    P. Joergensen, R. Koksbang, and P. Lindhardt,Acta Crystallogr. Sect. C: Cryst. Struct. Commun.,42, 1273 (1986);Chem. Abstr.,105, 144004 (1986).Google Scholar

Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • G. A. Atazhanova
    • 1
  • A. T. Kulyyasov
    • 1
  • A. D. Dembitskii
    • 1
  • V. A. Raldugin
    • 2
  • M. M. Shakirov
    • 2
  • I. Yu. Bagryanskaya
    • 2
  • Yu. V. Gatilov
    • 2
  • S. M. Adekenov
    • 1
  • G. A. Tolstikov
    • 2
  1. 1.Institute of PhytochemistryMinistry of Education and ScienceKaragandaRepublic of Kazakhstan
  2. 2.Novosibirsk Institute of Organic Chemistry, Siberian DivisionRussian Academy of SciencesNovosibirsk

Personalised recommendations