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Cellular retinol-binding protein in normal and neoplastic human mammary gland

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Abstract

The concentration of cellular retinol-binding protein (CRBP) was determined in samples of normal and neoplastic mammary gland, using a specific and sensitive radioimmunoassay. The CRBP concentration was significantly higher in neoplastic tissue, but detectable levels were also present in all samples of normal gland. Tubulo-ductal cancers had significantly lower CRBP levels than other cancer types. The CRBP concentration of the neoplastic tissue showed no correlation with the concentration of progesterone or estrogen receptor.

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Authors and Affiliations

  1. Department of Clinical Pathology, University of Lund, Malmö General Hospital, S-214 01, Malmö, Sweden

    G. Fex, F. Linell & O. Ljungberg

  2. Dept of Clinical Chemistry, University of Lund, Malmö General Hospital, S-214 01, Malmö, Sweden

    G. Fex, F. Linell & O. Ljungberg

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  1. G. Fex
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  2. F. Linell
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  3. O. Ljungberg
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Fex, G., Linell, F. & Ljungberg, O. Cellular retinol-binding protein in normal and neoplastic human mammary gland. Breast Cancer Res Tr 6, 131–136 (1985). https://doi.org/10.1007/BF02235744

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