The American Journal of Digestive Diseases

, Volume 12, Issue 1, pp 98–103 | Cite as

Concentration of gastric-juice proteins in a patient with Menetrier's disease

Report of a case
  • Irwin Katzka
  • Joan Glicken
  • J. Seckler
Case Reports


In a case of Menetrier's disease with hypoproteinemia the gastric-juice protein concentrations (Lowry) were 8.0 and 8.4 mg./ml., more than 4 times the values found in normal, hyper-, and and achlothydric patients.

Starch-block electrophoresis showed globulin peaks as well as an albumin peak resembling the distribution seen in normals. The finding of a high concentration of protein in gastric juice appears to be characteristic of hypoproteinemia associated with Menetrier's disease.


Public Health Albumin Electrophoresis Protein Concentration Gastric Juice 
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  1. 1.
    Lowry, O. H., Rosebrouch, N. J., Farr, A. L., andRandall, R. J. Protein measurement with the Folin phenol reagent.J Biol Chem 193:265, 1951.PubMedGoogle Scholar
  2. 2.
    Katzka, I., The protein distribution of gastric juice electrophoresis.Gastroenterology 36:593, 1959.PubMedGoogle Scholar
  3. 3.
    Citrin, Y., Sterling, K., andHalsted, J. A. The mechanism of hypoproteinemia associated with giant hypertrophy of the gastric mucosa.New Eng J Med 257:906, 1957.PubMedGoogle Scholar
  4. 4.
    Gordon, R. S. Exudative enteropathy.Lancet 1:325, 1959.CrossRefPubMedGoogle Scholar
  5. 5.
    Glass, G. B. J., andIshimori, A. Passage of serum albumin into the stomach.Amer J Dig Dis 6:103, 1961.CrossRefPubMedGoogle Scholar
  6. 6.
    Glass, G. B. J., Stephanson-Louis, L., Rich, M., andMitchell, S. E. “Paper Electrophoretic Analysis of Gastric Juice in Gastric Anacidity, Gastric Atrophy and Cancer of the Stomach.” InProceedings of World Congress Gastroenterology, 1958. Williams and Wilkins, Baltimore, 1959, p. 994.Google Scholar
  7. 7.
    Schwartz, M., andJarnum, S., Gastrointestinal protein loss in idiopathic (hypercatabolic) hypoproteinemia.Lancet 1: 327, 1959.CrossRefPubMedGoogle Scholar
  8. 8.
    Holman, H., Nickel, W. F., andSleisenger, M. H. Hypoproteinemia antedating intestinal lesions, and possibly due to excessive serum protein loss into the intestine.Amer J Med 27:963, 1959.CrossRefPubMedGoogle Scholar
  9. 9.
    Butz, W. C. Giant hypertrophy gastritis.Gastroenterology 39:183, 1960.PubMedGoogle Scholar
  10. 10.
    Schwartz, S., andSchwartz, M. Hypoalbuminemia in gastric carcinoma.Gastroenterology 38:769, 1960.PubMedGoogle Scholar
  11. 11.
    Richmond, V., Caputto, R., andWolf, S. Biochemical study of the large molecular constituents of gastric juice.Gastroenterology 29:1017, 1955.PubMedGoogle Scholar

Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1967

Authors and Affiliations

  • Irwin Katzka
    • 1
  • Joan Glicken
    • 1
  • J. Seckler
    • 1
  1. 1.From the Department of MedicineLong Island Jewish HospitalNew Hyde Park

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