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Chemistry of Natural Compounds

, Volume 35, Issue 2, pp 179–181 | Cite as

Reaction of 3β-chloro-5α,6α-epoxysteroids with trifluoroacetic acid

  • N. V. Kovganko
  • S. K. Ananich
Article
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Abstract

It has been established that on the interaction of the 5α,6α-epoxysteroids (1a−c) with trifluoroacetic acid in chloroform the 6-trifluoroacetates of the 5α,6β-diols (2a−c) are formed in high yield. The alkaline hydrolysis of the trifluoroacetates (2a−c) leads to the corresponding diols (3a−c).

Keywords

Organic Chemistry Chloroform Diol Trifluoroacetic Acid Alkaline Hydrolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    N. V. Kovganko, D. V. Drozdov, and S. K. Ananich,Khim. Prir. Soedin., 96 (1999).Google Scholar
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    T. Harayama, O. Sakurai, H. Fukushi, Y. Tezuka, and F. Yoneda,J. Chem. Soc., Perkin Trans. I, 2335 (1988).Google Scholar

Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • N. V. Kovganko
  • S. K. Ananich

There are no affiliations available

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