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Synthesis of14C-radioactively labeled samples of batriden

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Chemistry of Natural Compounds Aims and scope

Abstract

Samples of batriden (a drug based on gossypol) radioactively labeled with14C in different parts of the molecule have been synthesized. Pharmacokinetic investigations of the14C-batridens have enabled the mechanism of the action of the drug to be elucidated.

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Authors and Affiliations

  1. A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    V. N. Sumin, N. I. Baram & A. I. Ismailov

  2. Institute of Immunology, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    A. D. Sakhibov

Authors
  1. V. N. Sumin
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  2. A. D. Sakhibov
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  3. N. I. Baram
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  4. A. I. Ismailov
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Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 185–187, March–April, 1999.

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Sumin, V.N., Sakhibov, A.D., Baram, N.I. et al. Synthesis of14C-radioactively labeled samples of batriden. Chem Nat Compd 35, 165–167 (1999). https://doi.org/10.1007/BF02234925

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  • DOI: https://doi.org/10.1007/BF02234925

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