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Primary low-grade B cell non-hodgkin's lymphoma of MALT type simultaneously arising in the colon and in the lung

Report of a case

  • Case Reports
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Diseases of the Colon & Rectum

Abstract

Gastrointestinal lymphomas are the most common extranodal non-Hodgkin's lymphomas. Most gastrointestinal lymphomas are low-grade B cell lymphomas and originate from the mucosa-associated lymphoid tissue (mucosa-associated lymphoid tissue-type lymphoma or extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue type according to the Revised European American Lymphoma classification). Other mucosa-associated lymphoid tissue-type lymphomas arise in the salivary glands, thyroid gland, and in the lung (bronchus-associated lymphoid tissue). Here, we report the first case of a monoclonal mucosa-associated lymphoid tissue lymphoma with simultaneous manifestation in the colonic and bronchial mucosa in a 62-year-old patient. With mitoxantrone, chlorambucil, and prednisone polychemotherapy, a complete year-long remission was achieved.

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References

  1. Otter R, Bieger R, Kluin PM, Hermans J, Willemze R. Primary gastrointestinal non Hodgkin's lymphoma in a population-based registry. Br J Cancer 1989;60:745–50.

    Google Scholar 

  2. Azab MB, Henry-Amar M, Rougier P,et al. Prognostic factors in primary gastrointestinal Non-Hodgkin's Lymphoma. Cancer 1989;64:1208–17.

    Google Scholar 

  3. Koch P, Grothaus-Pinke B, Hiddemann W,et al. Primary lymphoma of the stomach: 3-years results of a prospective multicentre study. Ann Oncol 1997;8(Suppl 1):85–8.

    Google Scholar 

  4. Kiene J, Sezer O, Rasche H, Klempa I. Gastrointestinale Lymphome: Ergebnisse einer multimodalen Therapie bei 57 Patienten eines Zentrums. Langenbecks Arch Chir Suppl Kongressbd 1996;113:244–6.

    Google Scholar 

  5. Zighelboim J, Larson MV. Primary colonic lymphoma. Clinical presentation, histopathologic features, and outcome with combination chemotherapy. J Clin Gastroenterol 1994;18:291–7.

    Google Scholar 

  6. Isaacson PG. Gastrointestinal lymphoma. Hum Pathol 1994;25:1020–9.

    Google Scholar 

  7. L'Hoste RJ, Filippa DA, Lieberman PH, Bretsky S. Primary pulmonary lymphomas. Cancer 1984;54:1397–406.

    Google Scholar 

  8. Rüdiger T, Ott G, Ott MM, Muller-Deubert SM, Muller-Hermelink HK. Differential diagnosis between classic Hodgkin's lymphoma, T-cell-rich B-cell lymphoma, and paragranuloma by paraffin immunohistochemistry. Am J Surg Pathol 1998;22:1184–91.

    Google Scholar 

  9. Kuppers R, Zhao M, Rajewski K, Hansmann ML. Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction. Am J Pathol 1993;143:230–9.

    Google Scholar 

  10. Musshoff K. Klinische Stadieneinteilung der Nicht-Hodgkin-Lymphome. Strahlentherapie 1977;153:218–21.

    Google Scholar 

  11. Hiddemann W, Unterhalt M, Buske C, Sack H. Treatment of follicular follicle centre lymphomas: current status and future perspectives. J Intern Med Suppl 1997;740:55–62.

    Google Scholar 

  12. Skinner JM. Gastrointestinal lymphoma. Pathology 1985;17:193–203.

    Google Scholar 

  13. Lin KM, Penney DG, Mahmoud A, Chae W, Kolachalam RB, Young SC. Advantage of surgery and adjuvant chemotherapy in the treatment of primary gastrointestinal lymphoma. J Surg Oncol 1997;64:237–41.

    Google Scholar 

  14. Bäck H, Gustavsson B, Ridell B, Rödjer S, Westin J. Primary gastrointestinal lymphoma, incidence, clinical presentation, and surgical approach. J Surg Oncol 1986;33:234–8.

    Google Scholar 

  15. Isaacson PG, Wright DH. Extranodal malignant lymphoma arising from mucosa-associated lymphoid tissue. Cancer 1984;53:2515–24.

    Google Scholar 

  16. Isaacson PG. Extranodal Lymphomas: the MALT concept. Verh Dtsch Ges Pathol 1992;76:14–23.

    Google Scholar 

  17. Radaszkiewicz T, Dragosics B, Bauer P. Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Gastroenterology 1992;102:1628–38.

    Google Scholar 

  18. Law MM, Williams SB, Wong JH. Role of surgery in the management of primary lymphoma of the gastrointestinal tract. J Surg Oncol 1996;61:199–204.

    Google Scholar 

  19. Sonnen R, Calavrezos A, Grimm HA, Kuse R. Kombinierte konservative Behandlung von lokalisierten Magenlymphomen. Dtsch Med Wochenschr 1994;119:863–8.

    Google Scholar 

  20. Gobbi PG, Dionigi P, Barbieri F,et al. The role of surgery in the multimodal treatment of primary gastric non Hodgkin's lymphomas. A report of 76 cases and review of the literature. Cancer 1990;65:2528–36.

    Google Scholar 

  21. d'Amore F, Brincker H, Groenbaek K,et al. for the Danish Lymphoma Study Group. Non Hodgkin's lymphoma of the gastrointestinal tract: a population-based analysis of incidence, geographic distribution, clinicopathologic presentation features, and prognosis. J Clin Oncol 1994;12:1673–84.

    Google Scholar 

  22. Horning SJ. Low-grade lymphoma 1993: state of the art. Ann Oncol 1994;5(Suppl 2):23–7.

    Google Scholar 

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Author information

Authors and Affiliations

  1. From the Department of Gastroenterology, Bogenhausen Academic Teaching Hospital, Munich

    S. Sallach M.D., T. Schmidt M.D., C. Pehl M.D. &  W. Schepp M.D.

  2. the Department of Cardiology and Pulmology, Bogenhausen Academic Teaching Hospital, Munich

    S. Gallenberger M.D.

  3. the Department of Pathology, Bogenhausen Academic Teaching Hospital, Munich

    E. Keiditsch M.D.

  4. Pathology and Pathological Anatomy, University of Würzburg, Würzburg, Germany

    P. Starostik M.D. & G. Ott M.D.

Authors
  1. S. Sallach M.D.
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  2. T. Schmidt M.D.
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  3. C. Pehl M.D.
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  4. S. Gallenberger M.D.
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  5. E. Keiditsch M.D.
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  6. P. Starostik M.D.
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  7. G. Ott M.D.
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  8. W. Schepp M.D.
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Sallach, S., Schmidt, T., Pehl, C. et al. Primary low-grade B cell non-hodgkin's lymphoma of MALT type simultaneously arising in the colon and in the lung. Dis Colon Rectum 44, 448–452 (2001). https://doi.org/10.1007/BF02234748

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  • DOI: https://doi.org/10.1007/BF02234748

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