Pressure studies in the normal human jejunum
Intraluminal pressure changes of the human upper jejunum immediately distal to the ligament of Treitz were recorded in 22 healthy volunteers. Simultaneous recordings were obtained through 3 open-tip catheters, where orifices were 10 cm. apart. The effect of distal obstruction with an inflatable balloon was also studied. Tracings were analyzed quantitatively as well as for the appearance of their general pattern. Of the 3 methods of assessing motility quantitatively (numerical wave count, percent time activity, and planimetry), planimetry gave the most reliable results.
Obstruction by a balloon did not significantly increase bowel function, at least for the first 15 min., but the release of the obstruction was followed by significant decrease in activity.
Different waves and patterns were seen during this study. These were simple monophasic pressure waves or waves representing prolonged base line elevation. These waves were either single or repetitive, and were frequently indicative of correlated distal progression. Distal obstruction or release of the balloon did not influence the occurrence of caudal sequences of long outbursts of rhythmic activity, but greatly diminished the frequency of caudal sequences of simple monophasic waves.
KeywordsCatheter Pressure Wave Base Line Bowel Function Rhythmic Activity
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