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The jirgl test in the differential diagnosis of jaundice

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Summary

Jirgl's flocculation test for obstructive jaundice was evaluated in 101 tests in 70 patients, 54 of whom were jaundiced. There were 29.8% false positive tests among 47 cases of hepatitis, liver cirrhosis, and intrahepatic cholestasis of varying causes. In all 7 cases of extrahepatic obstruction, the Jirgl test was positive.

The test appears to be of value in jaundiced patients only when negative, strongly suggesting “medical” jaundice. A positive Jirgl test is of little differential diagnostic value because of the great number of false positive reactions in jaundice caused by liver disease.

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Authors and Affiliations

  1. From the Section of Gastroenterology, Department of Medicine, New York Medical College-Metropolitan Hospital Medical Center, New York, N. Y.

    William S. Rosenthal M.D. & Peter A. Douvres M.D.

Authors
  1. William S. Rosenthal M.D.
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  2. Peter A. Douvres M.D.
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Additional information

Supported in part by Clinical Research Center Grant AM-05576-03 from the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, U. S. Public Health Service, Bethesda, Md.

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Rosenthal, W.S., Douvres, P.A. The jirgl test in the differential diagnosis of jaundice. Digest Dis Sci 10, 300–305 (1965). https://doi.org/10.1007/BF02233421

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  • DOI: https://doi.org/10.1007/BF02233421

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