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The effect of glycopyrrolate on the course of symptomatic duodenal ulcer

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Summary

A double-blind controlled study of the effect of glycopyrrolate on 46 patients with duodenal ulcer is reported.

No beneficial effect of the drug over a period of 18–27 months could be demonstrated. Possible reasons for the difference between this study and that reported previously are discussed.

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References

  1. Sun, C. H. Long terra anticholinergic therapy for prevention of recurrences in duodenal ulcer.Amer J Dig Dis 9:706, 1964.

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  2. Jones, I. H. Riboflavine as an indicator of drug taking behavior.Med J Aust 1:5, 202, 1967.

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Author notes

  1. Hector Trevino M.D. (Fellow in Gastroenterology)

    Present address: Department of Medicine, Facultad de Medicina de la Universidad de Nuevo Leon, Monterrey, N. L., Mexico

  2. Juan Anderson M.D. (Fellow in Gastroenterology)

    Present address: Hospital de Clinicas-Sala IV, Universidad de Buenos Aires, Buenos Aires, Argentina

  3. Paula G. Davey M.D.

    Present address: St. Joseph's Mercy Hospital, Ann Arbor, Mich.

Authors and Affiliations

  1. From the Department of Internal Medicine, Section of Gastroenterology, University of Michigan Medical School, and the Veterans Administration Hospital, Ann Arbor, Mich.

    Hector Trevino M.D. (Fellow in Gastroenterology), Juan Anderson M.D. (Fellow in Gastroenterology), Paula G. Davey M.D. & Keith S. Henley M.D.

  2. the W. K. Kellogg Foundation, Battle Creek, Mich.

    Hector Trevino M.D. (Fellow in Gastroenterology)

Authors
  1. Hector Trevino M.D.
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  2. Juan Anderson M.D.
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  3. Paula G. Davey M.D.
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  4. Keith S. Henley M.D.
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Additional information

Our thanks are due to the A. H. Robins Co., Richmond, Va. for the supply of tablets and for a grant in aid of this study. We also with to thank Dr. W. A. Sodeman for his cooperation, and Mrs. H. Waite for clerical assistance.

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Trevino, H., Anderson, J., Davey, P.G. et al. The effect of glycopyrrolate on the course of symptomatic duodenal ulcer. Digest Dis Sci 12, 983–987 (1967). https://doi.org/10.1007/BF02233256

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  • DOI: https://doi.org/10.1007/BF02233256

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