Skip to main content
SpringerLink
Log in

Relationship between net water absorption and hexanoic acid absorption from the intact human jejunum

  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

Summary

The effect of net water absorption on the rate of disappearance of hexanoic acid from a 30-cm, test segment of jejunum in normal human subjects was studied. The results suggest that the disappearance rate of hexanoic acid is independent of water absorption. There was no change in fatty acid disappearance rate when water absorption was doubled, or when there was a reversal of water flow with secretion of water into the lumen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Greenberger, J. J., Ruppfrt, R. D., andTzagournis, M. Use of medium chain triglycerides in malabsorption.Ann Intern Med 66:727, 1967.

    PubMed  Google Scholar 

  2. Zurier, R. B., Hashim, S. A., andVan Itallie, T. B. Effect of medium chain triglyceride on cholestyramine-induced steatorrhea in man.Gastroenterology 49:490, 1965.

    PubMed  Google Scholar 

  3. Hashim, S. A., Roholt, H. B., andVan Itallie, T. B. Pancreatogenous steatorrhea treated with medium chain triglycerides.Clin Res 10:394, 1962.

    Google Scholar 

  4. Bennett, S. Intestinal absorptive capacity and site of absorption of fat under steady state conditions in the unanesthetized rat.Quart J Exp Physiol 49:210, 1964.

    Google Scholar 

  5. Jacobson, E. D., Bondy, D. C., Broitman, S. A., andFordtran, J. S. Validity of polyethylene glycol in estimating internal water volume.Gastroenterology 44:761, 1963.

    PubMed  Google Scholar 

  6. Fordtran, J. S., Rector, F. C., Ewton, M. F., Soter, N., andKinney, J. Permeability characteristics of the human small intestine.J Clin Invest 44:1935, 1965.

    PubMed  Google Scholar 

  7. Cooper, H. R., Levitan, R., Fordtran, J. S., andIngelfinger, F. J. A method for studying absorption of water and solute from the human small intestine.Gastroenterology 50:1, 1966.

    PubMed  Google Scholar 

  8. Hyden, S. A. A turbidimetric method for the determination of higher polyethyleneglycols in biological materials.Ann Agr Coll Sweden 22:139, 1955.

    Google Scholar 

  9. Baumgardt, B. R. Practical Observations on the Quantitative Analysis of Free Volatile Fatty Acids (VFA) in Aqueous Solutions by Gas-Liquid Chromatography. Department Bulletin, Department of Dairy Science, University of Wisconsin Bulletin. June 1964, p. 1.

  10. Dawson, A. M., Holdsworth, C. D., andWebb, J. Absorption of short chain fatty acids in man.Proc Soc Exp Biol Med 117:97, 1964.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. From the Gastroenterology Research Laboratory, New England Medical Center Hospital, Tufts University School of Medicine, Boston, Mass.

    Robert B. Zurier M.D., James F. Patterson M.D. & Ruven Levitan M.D.

Authors
  1. Robert B. Zurier M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. James F. Patterson M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ruven Levitan M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by a U. S. Public Health Service Grant AM-09332, by Gastroenterology training Grant 5TIAM5424 from the National Institute of Arthritis and Metabolic Diseases, and by Massachusetts Heart Association Grant 777.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zurier, R.B., Patterson, J.F. & Levitan, R. Relationship between net water absorption and hexanoic acid absorption from the intact human jejunum. Digest Dis Sci 13, 109–112 (1968). https://doi.org/10.1007/BF02232952

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02232952

Keywords

Search

Navigation