The American Journal of Digestive Diseases

, Volume 14, Issue 2, pp 96–106 | Cite as

Intraluminal pressure studies at different distances from the anus in normal subjects and in patients with the irritable colon syndrome

  • J. A. Ritchie
  • M. S. Tuckey


Three parameters of intraluminal pressure in the human rectum and pelvic colon have been recorded at different distances from the anal margin in the course of 56 observations in 25 normal subjects. These have been compared graphically with measurements taken from 183 observations in patients with the irritable colon syndrome. The 98 patients involved were divided into one group with painless diarrhea, another with spastic colon in whom colonic pain was the chief symptom, and a mixed group with both pain and diarrhea.

The pattern of localized motor activity found in patients with painless diarrhea resembled that seen in the normal bowel. There were also similarities between the curves for the group with spastic colon and the group with mixed irritable colon, and these were significantly different from those obtained from normal subjects and patients with painless diarrhea.

The findings tend to differentiate a consistently painless diarrhea from the remainder of the irritable colon syndrome.


Public Health Diarrhea Motor Activity Mixed Group Intraluminal Pressure 
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Copyright information

© Hoeber Medical Division • Harper & Row, Publishers, Incorporated 1969

Authors and Affiliations

  • J. A. Ritchie
    • 1
  • M. S. Tuckey
    • 1
  1. 1.From the Nuffield Department of Clinical MedicineNuffield Institute for Medical ResearchOxfordEngland

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