Newer horizons in the etiology of pancreatitis: Metabolic and endocrinologic factors
- 13 Downloads
1. Pancreatitis associated with alcoholism and biliary-tract disease account for etiology in only approximately two-thirds of the cases of chronic pancreatitis. The remainder comprise clinical varieties of pancreatitis of metabolic, vascular, and endocrinologic pathogenesis. These varieties are not as rare as previously thought.
2. Five case reports are presented illustrating silent, painless, hyperparathyroid-associated, hereditary-familial, and perhaps, hereditary-parathyroid-associated pancreatitis. The theoretical and clinical implications are discussed.
3. The importance of excluding parathyroid disease in all patients with pancreatic calculi is stressed.
4. A patient is presented who, in 7 years following sphincterotomy, has exhibited no roentgen, laboratory, or clinical evidence of deterioration of gallbladder function and no cholecystic inflammatory disease.
KeywordsPublic Health Pancreatitis Inflammatory Disease Chronic Pancreatitis Clinical Implication
Unable to display preview. Download preview PDF.
- 1.Bartholomew, L. G., andComfort, M. W. Chronic pancreatitis without pain.Proc. Staff Meet. Mayo Clin. 32:361, 1957.Google Scholar
- 2.Bartholomew, L. G. New concepts in pancreatic disease.Gastroenterology 36:122, 1959.Google Scholar
- 3.Cope, O., Culver, P. J., Mixter, C. G., andNardi, G. L. Pancreatitis: A diagnostic clue to hyperparathyroidism.Ann. Surg. 145:857, 1957.Google Scholar
- 4.Recant, L., andHartroft, W. S. Primary hyperparathyroidism, pancreatitis, and peptic ulcer.Am. J. Med. 23:953, 1957.Google Scholar
- 5.Jordan, G. L., Curd, G. W., Gyorkey, F., andDeBakey, M. E. Carcinoma of the parathyroid.A.M.A. Arch. Surg. 76:87, 1958.Google Scholar
- 6.Gross, J. B. Some recent developments pertaining to pancreatitis.Ann. Int. Med. 49:796, 1958.Google Scholar
- 7.Wang, C., Adlersberg, D., andFeldman, E. B. Serum lipids in acute pancreatitis.Gastroenterology 36:832, 1959.Google Scholar
- 8.Gross, J. B., andComfort, M. W. Chronic pancreatitis.Am. J. Med. 21:596, 1956.Google Scholar
- 9.Gross, J. B., Comfort, M. W., andWaugh, J. M. Painless single stone in pancreatic duct. Report of a case with steatorrheal diarrhea.Gastroenterology 32:126, 1957.Google Scholar
- 10.Peters, B. J., Lubitz, J. M., andLindert, M. C. F. Diffuse calcifications of the pancreas.A.M.A. Arch. Int. Med. 87:391, 1951.Google Scholar
- 11.Zuidema, P. J. Calcification and cirrhosis of pancreas in patients with deficient nutrition.Docum. Med. Geogr. Trop. Amst. 7:229, 1955; cited by McGeorge, B. P.,et al. Am. J. Roentgenol. 78:599, 1957.Google Scholar
- 12.Haverback, B. J., Bundy, H., andEdmondson, H. A. “The conversion of trypsinogen to trypsin in human pancreatic juice,” presented at the American Gastroenterological Association Annual Meeting at Atlantic City, N. J., June 1959.Google Scholar
- 13.Gross, J. B., Comfort, M. W., andUlrich, J. Abnormalities of serum and urinary amino acids in hereditary and non-hereditary pancreatitis.Tr. A. Am. Physicians 70:127, 1957.Google Scholar
- 14.Jackson, C. E. Hereditary hyperparathyroidism associated with recurrent pancreatitis.Ann. Int. Med. 49:829, 1959.Google Scholar