Crohn's disease of the duodenum (transmural duodenitis): Clinical manifestations
- 26 Downloads
Data from 11 patients with Crohn's disease of the duodenum (transmural duodenitis), seen from 1965–1970, are reported. For all, duodenal involvement predominated with a) symptoms of duodenal obstruction (6 patients); b) symptoms of duodenal ulceration (3 patients); c) or both (2 patients). Six had previous histories of transmural enteritis or colitis; for 5, duodenal involvement was the first manifestation of transmural enteritis. All subsequently had other involvement by transmural enteritis: 8 ileal, 5 colonic, 3 cutaneous fistulae and 3 perirectal abscesses. Ten had operations for duodenal disease and had bypass procedures; no vagotomy was done. Eight have done well and only 1 required further operations. Transmural duodenitis should be suspected for patients with symptoms of duodenal ulceration or obstruction and known transmural enteritis or colitis; duodenal involvement may be the first manifestation of transmural enteritis.
KeywordsPublic Health Clinical Manifestation Ileal Duodenal Ulceration Previous History
Unable to display preview. Download preview PDF.
- 2.Brooke BN: Granulomatous diseases of the intestine. Lancet 2:746–749, 1959Google Scholar
- 4.Lindner AE, Marshak RH, Wolf BS, et al: Granulomatous colitis: A clinical study. N Engl J Med 269:379–385, 1963Google Scholar
- 7.Idem: The clinical differentiation of transmural (regional) colitis from ulcerative colitis. Bibl Gastroenterol 9:94–103, 1970Google Scholar
- 8.Gottlieb C, Alpert S: Regional jejunitis. Am J Roentgenol Radium Ther Nucl Med 38:881–883, 1937Google Scholar
- 10.Brown CH, Sims JR Jr: Regional enteritis involving the duodenum: report of 2 cases. Cleve Clin Q 21:95–102, 1954Google Scholar
- 23.Friedman IH: Regional duodenitis. NY State J Med 67:461–464, 1967Google Scholar