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Crohn's disease of the duodenum (transmural duodenitis): Clinical manifestations

Report of 11 cases

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Abstract

Data from 11 patients with Crohn's disease of the duodenum (transmural duodenitis), seen from 1965–1970, are reported. For all, duodenal involvement predominated with a) symptoms of duodenal obstruction (6 patients); b) symptoms of duodenal ulceration (3 patients); c) or both (2 patients). Six had previous histories of transmural enteritis or colitis; for 5, duodenal involvement was the first manifestation of transmural enteritis. All subsequently had other involvement by transmural enteritis: 8 ileal, 5 colonic, 3 cutaneous fistulae and 3 perirectal abscesses. Ten had operations for duodenal disease and had bypass procedures; no vagotomy was done. Eight have done well and only 1 required further operations. Transmural duodenitis should be suspected for patients with symptoms of duodenal ulceration or obstruction and known transmural enteritis or colitis; duodenal involvement may be the first manifestation of transmural enteritis.

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Authors and Affiliations

  1. From the Departments of Gastroenterology, Anatomic Pathology and Colon and Rectal Surgery, The Cleveland Clinic Foundation and The Cleveland Clinic Educational Foundation, Cleveland, Oh.

    Richard G. Farmer MD, William A. Hawk MD & Rupert B. Turnbull Jr. MD

Authors
  1. Richard G. Farmer MD
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  2. William A. Hawk MD
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  3. Rupert B. Turnbull Jr. MD
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Additional information

This study supported in part by the following research funds: John M. Wilson Memorial, Louise Timken, Kay Williams, Noah Butkin, Burton Rawlins.

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Farmer, R.G., Hawk, W.A. & Turnbull, R.B. Crohn's disease of the duodenum (transmural duodenitis): Clinical manifestations. Digest Dis Sci 17, 191–198 (1972). https://doi.org/10.1007/BF02232289

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  • DOI: https://doi.org/10.1007/BF02232289

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