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Normal human rectal mucosa and its mechanism of repair

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Summary

1. The histologic appearance of 100 biopsy specimens of normal rectal mucosa has been studied.

2. The healing of healthy rectal mucosa after trauma has been examined.

3. Regeneration of entire crypts is not possible if the undifferentiated cells at the bases are destroyed.

4. Denuded areas are re-epithelialized by flattened cells that spread out from adjacent surviving crypts.

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Authors and Affiliations

  1. James Walker Memorial Hospital, Wilmington, N. C.

    George Lumb M.D. (M.R.C.P. Director of Clinical Laboratories)

Authors
  1. George Lumb M.D.
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Lumb, G. Normal human rectal mucosa and its mechanism of repair. Digest Dis Sci 5, 836–840 (1960). https://doi.org/10.1007/BF02232186

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  • DOI: https://doi.org/10.1007/BF02232186

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