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Colchicine induced remission in amyloid nephrotic syndrome

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Summary

An unusual case of reversible reactive amyloidosis (AA) is described. A patient in the course of lobar pneumonia developed acute transient nephrotic syndrome and renal failure. Renal and liver biopsy showed amyloidosis and positive immunohistochemistry stains for amyloid A protein.

The nephrotic syndrome resolved completely following 6 months of colchicine treatment and the urine is protein free after 6 years of follow-up.

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Authors and Affiliations

  1. Department of Medicine, Hadassah University Hospital, Mount Scopus, P.O. Box 24035, 91240, Jerusalem, Israel

    R. Oren M.D., Y. Naparstek & A. Rubinow

  2. Department of Pathology, Hadassah University Hospital Ein Kerem, Jerusalem, Israel

    G. Pizov

Authors
  1. R. Oren M.D.
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  2. G. Pizov
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  3. Y. Naparstek
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  4. A. Rubinow
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Oren, R., Pizov, G., Naparstek, Y. et al. Colchicine induced remission in amyloid nephrotic syndrome. Clin Rheumatol 12, 532–534 (1993). https://doi.org/10.1007/BF02231786

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  • DOI: https://doi.org/10.1007/BF02231786

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