Comparison between the effect of pentagastrin and Histalog on gastric acid secretion
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Fifty subjects with a wide range of maximal gastric secretory output were tested, using Histalog (2.5 mg/kg intramuscularly) as the stimulant on one day and pentagastrin (6 µg/kg subcutaneously) on another day. Gastric output was collected for 2 hours after each injection. The pentagastrin test used in this study gave virtually the same value for 30-minute acid output as the Histalog test and could be shortened to 45 minutes post-injection without loss of accuracy. The side effects of pentagastrin were trivial and transitory.
KeywordsPublic Health Gastric Acid Acid Secretion Gastric Acid Secretion Acid Output
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