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The American Journal of Digestive Diseases

, Volume 17, Issue 8, pp 713–719 | Cite as

Comparison between the effect of pentagastrin and Histalog on gastric acid secretion

  • I. G. M. Cleator
  • J. L. Stoller
  • F. R. C. Johnstone
  • I. B. Holubitsky
  • R. C. Harrison
Article

Abstract

Fifty subjects with a wide range of maximal gastric secretory output were tested, using Histalog (2.5 mg/kg intramuscularly) as the stimulant on one day and pentagastrin (6 µg/kg subcutaneously) on another day. Gastric output was collected for 2 hours after each injection. The pentagastrin test used in this study gave virtually the same value for 30-minute acid output as the Histalog test and could be shortened to 45 minutes post-injection without loss of accuracy. The side effects of pentagastrin were trivial and transitory.

Keywords

Public Health Gastric Acid Acid Secretion Gastric Acid Secretion Acid Output 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Harper & Row, Publishers 1972

Authors and Affiliations

  • I. G. M. Cleator
    • 1
  • J. L. Stoller
    • 1
  • F. R. C. Johnstone
    • 1
  • I. B. Holubitsky
    • 1
  • R. C. Harrison
    • 1
  1. 1.Department of SurgeryUniversity of British Columbia, Vancouver General HospitalVancouver 9Canada

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