The American Journal of Digestive Diseases

, Volume 2, Issue 11, pp 663–668 | Cite as

Evidence of increased intestinal absorption of molecular sucrose in sprue

  • Rafael SantiniJr.
  • E. Perez-Santiago
  • Jose Martinez-de Jesus
  • C. E. ButterworthJr.


It has been found that patients with sprue excrete significantly greater quantities of intact sucrose in the urine after an oral dose of sucrose than do normal subjects. The urine of normal persons becomes free of sucrose after a 10-hour fast, but patients with sprue may exhibit sucrosuria throughout a 24-hour fast. Diminished hydrolysis of sucrose and increased intestinal permeability are mentioned as possible explanations for the findings.


Public Health Permeability Hydrolysis Sucrose Oral Dose 
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Copyright information

© Paul B. Hoeber, Inc. 1957

Authors and Affiliations

  • Rafael SantiniJr.
    • 1
  • E. Perez-Santiago
    • 1
  • Jose Martinez-de Jesus
    • 1
  • C. E. ButterworthJr.
    • 1
  1. 1.From the U. S. Army Tropical Research Medical LaboratorySan JuanP. R.

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