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Serum iron and gastric acidity in gastric carcinoma, peptic ulcer, and other diseases

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Summary

Seventy-five patients with various diseases including gastric cancer, other neoplasms, liver disorders, peptic ulcers, and miscellaneous chronic diseases were studied to determine if a correlation existed between serum iron values and gastric acidity. It was found that the average serum iron values in patients with gastric anacidity, gastric carcinoma, and anemia were lower than those of patients with other neoplasms, peptic ulcers, or miscellaneous nonmalignant diseases. The absorption of iron and the relation between gastric acid and the serum iron values obtained in this study have been briefly discussed.

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References

  1. Christian, E. R. Behaviour of serum iron in various diseases of the liver.A.M.A. Arch. Int. Med. 94:22, 1954.

    Google Scholar 

  2. Stone, C. M., Jr., andRumball, J. M. An evaluation of the serum iron in liver disease.Ann. Int. Med. 43:229, 1955.

    PubMed  Google Scholar 

  3. Greenberg, L. D., andRinehart, J. F. Serum iron levels in rhesus monkeys with chronic vitamin C deficiency.Proc. Soc. Exper. Biol. & Med. 88:325, 1955.

    Google Scholar 

  4. Feldthusen, U., andLassen, N. A. Serum iron after coronary occlusion and injuries.Acta med. scandinav. 150:53, 1954.

    Google Scholar 

  5. Hagberg, B. Studies on the Plasma Transport of Iron. Thesis, Uppsala, 1953.

  6. Belsasso, E. Blood iron levels in neoplasms.Rass. giuliana med., Trieste, 10:2, 1954.

    Google Scholar 

  7. Keiderling, W., andScharpf, H. The clinical significance of the determination of serum iron and copper in neoplastic diseases.Munchen. med. Wchnschr. 95:437, 1953.

    Google Scholar 

  8. Fredrikson, K. A. The significance of serum iron in the differential diagnosis between gastric carcinoma and peptic ulcer.Acta med. scandinav. 146:259, 1953.

    Google Scholar 

  9. Grace, W. J., Doig, R. K., andWolff, H. G. Absorption of iron from the gastrointestinal tract.J. Clin. Nutrition 2:162, 1954.

    Google Scholar 

  10. Moore, C. V.,et al. Studies of iron transportation and metabolism: IV. Observations on the absorption of iron from the gastrointestinal tract.J. Clin. Invest. 18:553, 1939.

    Google Scholar 

  11. Dubach, R., Callender, St.E., andMoore, C. V. Studies on iron transportation and metabolism: VI. Absorption of radioactive iron in patients with fever and with anemias of varied etiology.Blood 3:526, 1948.

    Google Scholar 

  12. Heinrich, G. Disturbance of intestinal iron absorption after gastric resection.Chirurg. 25:490, 1954.

    PubMed  Google Scholar 

  13. Barer, A. P., andFowler, W. M. Influence of gastric acidity and degrees of anemia on iron retention.A.M.A. Arch. Int. Med. 59:785, 1937.

    Google Scholar 

  14. Heilmeyer, L., andPlotner, K. Iron deficiency states and their treatment.Klin. Wchnschr. 15:1669, 1936.

    Article  Google Scholar 

  15. Clinical Manual. Klett Mfg. Co., New York.

  16. Segal, H. L. Determination of gastric acidity without intubation: Clinical evaluations of quininium exchange indicator compound.M. Clin. North America 35:593, 1951.

    Google Scholar 

  17. Cantarow, A., andTrumper, M. Clinical Biochemistry. (ed. 5) Philadelphia, Saunders, 1955.

    Google Scholar 

  18. Bateman, J. C. Klopp, C. T., andMiesfeld, P. Serum iron response to pituitary adrenal agents in normal and in cancer patients.Blood 7:1093, 1952.

    PubMed  Google Scholar 

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Author information

Author notes

  1. Margaret H. Edwards M.D.

    Present address: , 224 West State Street, Trenton 8, N. J.

Authors and Affiliations

  1. From the Departments of Oncology and Pathology, Woman's Medical College of Pennsylvania, Philadelphia, Pa

    Margaret H. Edwards M.D., Leonard J. Kimmelman Ph.D. & Charlotte Sokol M.D.

Authors
  1. Margaret H. Edwards M.D.
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  2. Leonard J. Kimmelman Ph.D.
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  3. Charlotte Sokol M.D.
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Additional information

Died June 26, 1955.

Aided by grants from Lederle Medical Student Research Fellowship, and United States Public Health Service Medical Student Research Fellowship.

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Edwards, M.H., Kimmelman, L.J. & Sokol, C. Serum iron and gastric acidity in gastric carcinoma, peptic ulcer, and other diseases. Digest Dis Sci 2, 454–466 (1957). https://doi.org/10.1007/BF02231316

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  • DOI: https://doi.org/10.1007/BF02231316

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