The American Journal of Digestive Diseases

, Volume 17, Issue 5, pp 463–472 | Cite as

Cirrhosis: Morphologic dynamics for the nonmorphologist

  • Henry D. Appelman
Clinical Seminar


Cirrhosis is an irreversible end-stage liver disease characterized by septate scars dividing a distorted liver into nodules. It generates through a sequence of dynamic changes and once it develops, it may alter its appearance through variations in secondary factors, such as injury and nutrition. The different classification schemes have, unfortunately, only served to make cirrhosis static in our thinking. Stationary morphologic characteristics are of value only if they can be correlated with etiology.


Public Health Nodule Liver Disease Morphologic Characteristic Classification Scheme 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Paul B. Hoeber, Inc. 1972

Authors and Affiliations

  • Henry D. Appelman
    • 1
  1. 1.From the Department of PathologyUniversity of Michigan Medical SchoolAnn Arbor

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