Skip to main content
Log in

Relationship between blood amylase and factors affecting carbohydrate metabolism

I. The regulation of blood amylase level in subjects without pancreatic disease

  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

Conclusions

The blood amylase level in subjects without pancreatic disease has been shown to change following the administration of drugs that affect carbohydrate metabolism. In general, the blood amylase falls in states during which there is increased utilization of sugar and rises following the administration of drugs that diminish the utilization of carbohydrate.

The normal blood amylase is regulated by extrapancreatic processes, the site of which remain obscure at present.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Somogyi, M. Blood diastase as an indicator of liver disease.Proc. Soc. Exper. Biol. Med. 32:538, 1937.

    Google Scholar 

  2. Reid, E., andMyers, V. C. Studies on animal diastases: IV. The effect of insulin on the diastatic activity of the blood in diabetes.J. Biol. Chem. 99:607, 1933.

    Google Scholar 

  3. Somogyi, M. Blood diastase in health and diabetes.J. Biol. Chem. 134:315, 1940.

    Google Scholar 

  4. Cope, O.,et al., Endocrine function and amylase activity.Endocrinology 25:236, 1939.

    Google Scholar 

  5. Somogyi, M. Diastase activity of human blood.Arch. Int. Med. 67:665, 1941.

    Google Scholar 

  6. Nelson, N. A photometric adaptation of the Somogyi method for the determination of glucose.J. Biol. Chem. 153:375, 1944.

    Google Scholar 

  7. Grossman, M. I. Experimental pancreatitis.A.M.A. Arch. Int. Med. 96:298, 1955.

    Google Scholar 

  8. Reid, E., Quigley, J. P., andMyers, V. C. Studies on animal diastase: V. Blood and tissue diastases with special reference to the depancreatized dog.J. Biol. Chem. 99:615, 1933.

    Google Scholar 

  9. McGeachin, R. L., andGleason, J. R. Extra-pancreatic, extra-salivary amylase in the rat.Fed. Proc. 16:219, 1957.

    Google Scholar 

  10. Fallis, L. S., andSzilagyi, D. E. Some observations on metabolic changes after total pancreatico-duodenectomy.Ann. Surg. 128:639, 1948.

    Google Scholar 

  11. Reid, C., andNarayama, B. Studies on blood and diastase: Factors which cause variations in amount of diastase in blood.Quart. J. Exper. Physiol. 20:305, 1930.

    Google Scholar 

  12. Lee, M., andRichter, D. Liver amylase and hyperlipaemia.Biochem. J. 34:353, 1940.

    Google Scholar 

  13. Taubenhaus, M., andSoskin, S. On the mechanism of insulin resistance in toxemic states.J. Clin. Endocrinol. 2:171, 1942.

    Google Scholar 

  14. Bierman, E. L., andDole, V. P. Action of insulin on release of fatty acids from tissue stores.Fed. Proc. 16:11, 1957.

    Google Scholar 

  15. Dreiling, D. A., andDierman, E. L. Correlation between plasma amylase activity and concentration of plasma non-esterified fatty acids (NEFA).Proc. Soc. Exper. Biol. & Med. 95:496, 1957.

    Google Scholar 

  16. Pfeffer, R. E., andHinton, J. W. Some relationships between adrenal medullary and cortical substances and exocrine secretion of the pancreas.Gastroenterology 31:746, 1957.

    Google Scholar 

  17. Dreiling, D. A., Druckerman, L. J., andHollander, F. The effect of complete vagisection and vagal stimulation on pancreatic secretion in man.Gastroenterology 20:578, 1952.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

The glucagon used in this study was furnished by the Eli Lilly Company, Indianapolis, Ind.

The Orinase used in this study was furnished by the Upjohn Company, Kalamazoo, Mich.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dreiling, D.A., Janowitz, H.D., Marshall, D. et al. Relationship between blood amylase and factors affecting carbohydrate metabolism. Digest Dis Sci 3, 214–219 (1958). https://doi.org/10.1007/BF02231268

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02231268

Keywords

Navigation