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Gastric blood flow in restraint stress

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Abstract

Alterations in gastric mucosal hemodynamics during the development of restraint-induced gastric erosions in the rat were studied using the indicator fractionation technic with86Rb. Cardiac output, gastric flow fractions and gastric blood flow were determined in rats subjected to zero (control), 1/2, 4 and 24 hours of restraint. No correlation was found between gastric mucosal blood flow changes and the natural development of restraint erosions. The possible role of local microcirculatory adjustments, independent of total mucosal flow, in the genesis of restraint lesions is discussed.

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Authors and Affiliations

  1. From the Medical Service, Veterans Administration Hospital (Wadsworth), 90073, Los Angeles, Calif

    Paul H. Guth MD

  2. the Department of Medicine, UCLA School of Medicine, 90024, Los Angeles, Calif

    Paul H. Guth MD

Authors
  1. Paul H. Guth MD
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Supported by Veterans Administration research funds.

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Guth, P.H. Gastric blood flow in restraint stress. Digest Dis Sci 17, 807–813 (1972). https://doi.org/10.1007/BF02231152

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  • DOI: https://doi.org/10.1007/BF02231152

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