The American Journal of Digestive Diseases

, Volume 5, Issue 8, pp 739–750 | Cite as

Whipple's disease

Report of a case
  • Helen D. Van Vactor
  • Bernard D. Rosenak
Case Reports


A typical case of Whipple's disease is reported, substantiated by histopathologic study. Treatment with steroids has been used with good results. A prolonged clinical remission has occurred, although persistance of pathologic changes in the small intestine has been demonstrated. This disease is a generalized one with polyserositis and malabsorption, the etiology of which is unknown. A genetic factor has been suggested, with the presence of a basic defect in intestinal cell absorption. That it may represent a general sensitivity reaction with inflammation, is possible. It may be amenable to steroid therapy.


Public Health Steroid Small Intestine Genetic Factor Pathologic Change 
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Copyright information

© Paul B. Hoeber, Inc. 1960

Authors and Affiliations

  • Helen D. Van Vactor
    • 1
  • Bernard D. Rosenak
    • 1
  1. 1.From the Department of MedicineIndiana University School of MedicineIndianapolis

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