Summary
Lyme arthritis, caused by the tick-borne spirochete Borrelia burgdorferi, produces typically intermittent episodes of arthritis of the larger joints, usually the knee joints. A number of patients, however, develop arthritis more closely resembling Reiter's syndrome, i.e., heel and ankle involvement. We studied the clinical features of ten patients who developed arthritis after a tick bite and who had shown erythema migrans and related it to the presence of evidence of Chlamydia trachomatis infection. Along with typical signs of Lyme arthritis we observed heel and ankle involvement. Chlamydia trachomatis was found in smears in 4 cases, whereas no patient had antichlamydial antibodies. However, evidence of Chlamydia trachomatis did not correlate with signs considered typical of Reiter's syndrome. Therefore, Lyme arthritis may have some arthritic manifestations resembling Reiter's syndrome, but this seems unrelated to the presence of Chlamydia trachomatis. Moreover, the arthritis is not associated with HLA-B27.
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References
Steere, A.C., Malawista, S.E., Snydman, D.R. et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum 1977, 20, 17.
Dekonenko, E.J., Steere, A.C., Berardi, U.P., Kravchuk, L.N. Lyme borreliosis in the Soviet Union: a cooperative US-USSR report. J Infect Dis 1988, 158, 748–753.
Steere, A.C. Clinical definitions and differential diagnosis of Lyme arthritis. Scand J Infect Dis Suppl 1991, 77, 51–54.
Herzer, P. Joint manifestations of Lyme borreliosis in Europe. Scand J Infect Dis Suppl 1991, 77, 55–63.
Rahn, D.W., Craft, J. Lyme disease. Rheum Dis Clin North Amer 1990, 16, 601–615.
Ciesielski, C.A., Markowitz, L.E., Harsley, R. et al. Lyme disease surveillance in the United States. 1983–1986. Rev Infect Dis Suppl 6 1989, 11, 1435–1441.
Stanek, G. The epidemiology of Borrelia burgdorferi infections. In: New Antibacterial Strategies. Proceedings of the 1st Symposium, Hertfordshire 1990, 19–29.
Prohaska, E., Kristoferitsch, W., Stanek, G. Spinal involvement in Lyme borreliosis. Zbl Bakt 1989 Suppl 18, 261–262.
Kinigadner, U., Mur, E., Most, J. et al. Borrelia infection as a possible cause of HLA-B27 negative sacroiliitis. J Rheumatol 1991, 18, 484–485.
Weyand, C.M., Goronzy, J.J. Immune responses to Borrelia burgdorferi in patients with reactive arthritis. Arthritis Rheum 1989, 32, 1057–1064.
Arnett, F. The Lyme spirochete: another cause of Reiter's syndrome? Arthritis Rheum 1989, 32, 1182–1184.
Shatkin, A. Chlamydial infections in Russia and former USSR. In: Proceedings of the Europ Soc for Chlamydia Research, Stockholm 1992, 283–285.
Steere, A.C., Schoen, R.T., Taylor, E. The clinical evolution of Lyme arthritis. Ann Intern Med 1987, 107, 725–731.
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Lesnyak, O., Sokolova, L., Starikova, T. et al. Does chlamydia trachomatis influence manifestations of lyme arthritis?. Clin Rheumatol 15, 353–357 (1996). https://doi.org/10.1007/BF02230357
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DOI: https://doi.org/10.1007/BF02230357