Abstract
3-(N-morpholino)-3-cyanoquinuclidine has been shown to form only 1-methyl-3-(N-morpholino)-3-cyanoquinuclidinium iodide or 1-benzyl-3-(N-morpholino)-3-cyanoquinuclidinium chloride when treated with iodomethane (1∶1 or 1∶2.3) or benzene chloride (1∶1), respectively. The direction of quarternization is determined using1H NMR spectroscopy.
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Alekseeva, N.N., Koikov, L.N. Quarternization of 3-(N-morpholino)-3-cyanoquinuclidine. Pharm Chem J 29, 146–147 (1995). https://doi.org/10.1007/BF02226531
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DOI: https://doi.org/10.1007/BF02226531