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Derivatives of natural amino acids as radioprotectors (review)

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References

  1. A. S. Mozzhukhin, F. Yu. Rachinskii, and L. I. Tank,The Chemical Prophylaxis of Acute Radiation Sickness [in Russian], Medgiz, Leningrad (1961).

    Google Scholar 

  2. A. S. Mozzhukhin and F. Yu. Rachinskii,The Chemical Prophylaxis of Acute Radiation Lesions [in Russian], 1st Edition, Atomizdat, Moscow (1964).

    Google Scholar 

  3. E. F. Romantsev,Radiation and Chemical Protection [in Russian], Atomizdat, Moscow (1968).

    Google Scholar 

  4. E. F. Romantsev, V. D. Blokhina, Z. I. Zhulanova, N. N. Koshcheenko, and I. V. Filipovich,The Biological Bases of the Action of Radioprotective Agents [in Russian], Atomizdat, Moscow (1980).

    Google Scholar 

  5. E. F. Romantsev,The Chemical Protection of Organic Systems from Ionizing Radiation [in Russian], Atomizdat, Moscow (1978).

    Google Scholar 

  6. P. G. Zherebchenko,The Antiradiation Properties of Indolylalkylamines [in Russian], Atomizdat, Moscow (1971).

    Google Scholar 

  7. D. L. Klayman and E. C. Copeland, “Design of antiradiation agents,” in:Medical Chemistry. Ser. Monogr., G. de Van (ed.), Acad. Press, New York (1975), Vol. 11, pp. 81 - 142.

    Google Scholar 

  8. N. N. Suvorov and V. S. Shashkov,The Chemistry and Pharmacology of Substances for the Prophylaxis of Radiation Lesions [in Russian], Atomizdat, Moscow (1975).

    Google Scholar 

  9. P. G. Saksonov, V. S. Shashkov, and P. V. Sergeev,Radiation Pharmacology [in Russian], Meditsina, Moscow (1976).

    Google Scholar 

  10. V. G. Vladimirov and T. G. Zaitseva,Farmakol. Toksikol., No. 2, 244 - 249 (1980).

    Google Scholar 

  11. V. G. Vladimirov and T. K. Dzharakyan,Radioprotective Effects in Animals and Humans [in Russian], énergoizdat, Moscow (1982).

    Google Scholar 

  12. V. G. Vladimirov, I. I. Krasil'nikov, and O. V. Arapov,Radioprotectors: Structure and Function [in Russian], Naukova Dumka, Kiev (1989).

    Google Scholar 

  13. E. I. Vorob'ev, V. I. Efimov, V. S. Shashkov, and A. V. Sedov,Kosm. Biol. Aviakosm. Med.,1, 3 - 9 (1981).

    Google Scholar 

  14. L. M. Rozhdestvenskii, A. G. Sverdlov, I. B. Smirnova, V. M. Fedoseev, and N. G. Khrushchev,Problems of Natural and Modified Radiosensitivity [in Russian], Nauka, Moscow (1983).

    Google Scholar 

  15. V. G. Yashchunskii,Usp. Khimii,44, 531 - 574 (1975).

    Google Scholar 

  16. V. G. Yashchunskii and V. Yu. Kovtun,Usp. Khimii,54, 126 - 161 (1985).

    Google Scholar 

  17. H. M. Part, E. B. Tyree, R. L. Straube, and D. E Smith,Science,110(2852), 213 - 217 (1949).

    Google Scholar 

  18. H. M. Patt,Physiol. Rev.,33, 35 - 43 (1953).

    Google Scholar 

  19. M. Sarezi, A. Hoxha, and S. Mehilli,Bull. Univ. Tiranes. Ser. Shkencat Mjekesore,22(4), 111 - 117 (1982).

    Google Scholar 

  20. V. G. Yakovlev and I. I. Ivanov,Med. Radiol.,3(5), 14 - 20 (1958).

    Google Scholar 

  21. A. Holleandr and D. C. Doherty,Radiation Damage and Sulfhydryl Compounds, Vienna (1969), p. 1.

  22. Akaboshi, et al.,Chem. Pharm. Bull. (Tokyo),20, 721 - 725 (1972).

    Google Scholar 

  23. D. L. Klayman, M. M. Grenan, and D. P. Jacobs,J. Med. Chem.,12, 510 - 512 (1969).

    Google Scholar 

  24. J. P. Weidner and S. S. Block,J. Med. Chem.,15(5), 564 - 567 (1985).

    Google Scholar 

  25. B. J. Sweetman, M. M. Vestling, S. T. Ticaric, P. L. Kelly, and L. Field,J. Med. Chem.,14(9), 868 - 872 (1971).

    Google Scholar 

  26. H. Nagate, T. Sugahara, and T. Tanaka,J. Rad. Res.,13, 163 - 169 (1972).

    Google Scholar 

  27. A. Santa, E. Mandi, and By Benko, in:Abstrs. of the 12th Annual Meeting of Eur. Soc. for Rad. Biol., Budapest (1976), p. 126.

  28. T. Sugahara, in:Radioprotection: Chemical Compounds, Biological Means, Basel (1977), p. 53.

  29. T. Sugahara,Jap. Med. News, No. 72, 11 (1971).

    Google Scholar 

  30. Y. Tanaka and T. Sugahara,J. Rad. Res.,11, 116 (1970).

    Google Scholar 

  31. M. L. Gupta, M. R. Saini, and R. P. Singh,Geobios,10(5), 234 - 235 (1983).

    Google Scholar 

  32. M. M. Konstantinova and L. Rivez,Radiobiologiya,17(6), 839 - 843 (1977).

    Google Scholar 

  33. R. M. Bhagat and A. Kumar,Natl. Acad. Sci. Lett.,5(11), 387 - 389 (1982).

    Google Scholar 

  34. R. M. Bhagat,Radiobiol. Radiother.,28(6), 811–814.

  35. P. K. Dev, S. M. Gupta, P. K. Goyal, G. Mehta, and B. Pareek,Strahlentherapie,157(8), 553 - 555 (1981).

    Google Scholar 

  36. P. K. Goyal and P. K. Dev,Strahlentherapie,159(4), 239 - 244 (1983).

    Google Scholar 

  37. A. S. Khan, J. Sharma, B. P. Pareek, and H. C. Bhartiga,Radiobiol. Radiother.,25(4), 579 - 583 (1984).

    Google Scholar 

  38. A. Kumar and R. M. Bhagat,Radiobiol. Radiother.,47(5), 635 - 638 (1981).

    Google Scholar 

  39. A. Kumar and P. U. Devi,Radiobiol. Radiother.,24(2), 231 - 234 (1983).

    Google Scholar 

  40. A. Kumar and P. U. Devi,J. Neul. Med. Allied Sci.,27(1), 9 - 12 (1983).

    Google Scholar 

  41. V. B. Mathur, P. U. Devi, and K. S. Bisht,Radiobiol. Radiother.,27(4), 479 - 484 (1986).

    Google Scholar 

  42. M. R. Saini and P. U. Devi,Indian J. Exper. Biol.,179, 949 - 953 (1979).

    Google Scholar 

  43. Y. Robbe,Radioprotection,7, 229 - 236 (1973).

    Google Scholar 

  44. M. R. Landauer, H. R. Davis, J. D. Dominitz, and J. F. Weise,Pharmacol. Ther.,39(1–3), 97 - 100 (1988).

    Google Scholar 

  45. N. J. Tarbell, M. Rosenblatt, D. A. Amoto, and S. Hellman,Radiother. Oncol.,7(1), 77 - 80 (1986).

    Google Scholar 

  46. V. G. Yakovlev, E. N. Yartsev, A. M. Orlov, M. I. Glinskaya, and S. D. Novosel'tseva,2nd Ural Conf. “Synthesis and Studies of the Properties and Uses of Detoxified Compounds” [in Russian], Sverdlovsk (1971), p. 65.

  47. S. P. Grozdov,Radiobiologiya,27(5), 657 - 662 (1987).

    Google Scholar 

  48. W. Chapman and E. Croricite,Proc. Soc. Exp. Biol Med.,75. 318 - 331 (1950).

    Google Scholar 

  49. L. Révész and E. P. Malaise,Biochem. Physiol. Toxicol. Clin. Aspects, 5th Karolinsaka Inst. Nobel Conf. 1982 (published 1983), pp. 163–173.

  50. L. Révész and H. Modig,Nature,207(49995), 430 - 431 (1965).

    Google Scholar 

  51. T. Akiyama, K. Tanaka, K. Bessho, and F. Yoneda,Chem. Pharm. Bull.,38(10), 2893 - 2895 (1990).

    Google Scholar 

  52. K. Hanada, R. W. Grange, and M. J. Connor,J. Invest. Dermatol.,96(6), 834 - 840 (1991).

    Google Scholar 

  53. Hsu Hsue Yin, Yu Hsin Su, and Ho You Hui,Ho Tzu Ko Hsueh,27(3), 189 - 196 (1990).

    Google Scholar 

  54. A. J. Minchinton and D. J. Chaplin,Int. J. Radiat. Biol.,59(6), 1425 - 1433 (1991).

    Google Scholar 

  55. Wilner Itamar and Lapidot Noa,J. Am. Chem. Soc.,113(9), 3625 - 3626 (1991).

    Google Scholar 

  56. J. A. Fuchs and M. R. Warner,J. Bacteriol.,124(1), 140 - 148 (1975).

    Google Scholar 

  57. M. L. Morse and R. H. Dahl,Nature,217(5646), 660 - 662 (1978).

    Google Scholar 

  58. M. Edgren, A. Larsson, K. Nilsson, L. Révész, and O. C. A. Scott,Int. J. Radiat. Biol.,37(3), 299 - 306 (1980).

    Google Scholar 

  59. M. M. Konstantinova, A. A. Minin, and I. V. Nekrasova,Radiobiologiya,21(2), 277 - 280 (1981).

    Google Scholar 

  60. J. B. Bioglav, M. E. Yarnes, E. R. Epp, E. P. Clark, S. W. Tuttle, and K. D. Held,Drug Metab. Rev.,20(1), 1 - 12 (1989).

    Google Scholar 

  61. A. Chatterjee, M. Jacob-Roman, and B. Mahapattra,Mutat. Res.,214(2), 207 - 213 (1989).

    Google Scholar 

  62. A. Chatterjee, M. Jacob-Roman, and B. Mahapattra,Mutat. Res.,215, 230 (1990).

    Google Scholar 

  63. M. Dutta and R. Mallick,Cell. Chromosome Res.,8(1), 12 - 16 (1985).

    Google Scholar 

  64. M. Edgren, L. Revesz, and H. Modig,Int. J. Radiat. Biol.,40(4), 355 - 363 (1981).

    Google Scholar 

  65. H. Modig and L. Revesz,Int. J. Radiat. Biol.,13(5), 469 - 474 (1967).

    Google Scholar 

  66. A. Nishimura, M. Hashimoto, Konnok, Y. Ohta, S. Tahara, and H. Z. Nishimura,Z. Naturforsch. C. Biosci.,350(9–10), 726 - 728 (1980).

    Google Scholar 

  67. J. Oiry, J. Y. Pue, J. L. Imbach, M. Fatome, H. Sentenac-Roumanou, and C. Lion,J. Med. Chem.,29(11), 2217 - 2225 (1986).

    Google Scholar 

  68. People's Republic of Bulgaria Invenor's Cerificate No. 26440, T. P. Pantev and I. L. Isakov.

  69. T. P. Pantev, S. P. Topalova, and I. L. Isakov,Farmakol. Toksikol., No. 4, 476 - 478 (1981).

    Google Scholar 

  70. E. N. Goncharenko, S. V. Stoev, S. V. Antonova, and E. é. Graevskaya,Radiobiologiya,22(2), 252 - 255 (1982).

    Google Scholar 

  71. A. M. Rusakov, G. N. Alekseeva, M. B. Kolesova, L. Stanik, K. M. Nodar, and L. D'erd', in:Reports of the Central Science Research Institute of X-Radiology (1968), p. 6.

  72. R. Granger, H. Orzabasi, and V. Robbe,Trav. Soc. Pharm. Monypellier,25, 3050 (1966);Ros. Zh. Khim.,8, 334 (1968).

    Google Scholar 

  73. V. Varteresz, L. Sztanyik, and K. Naror,Radiat. Prot. Sensitivization Proc. 2nd Int. Symp. 1969 (Published 1970), pp. 325–329.

  74. F. L. Carrol and M. E. Wall,J. Pharm. Sci.,59(9), 1350 - 1352 (1970).

    Google Scholar 

  75. H. Melching and C. Streffer,Juckers Fostschrift. d. Arzneimittelforsch.,8(9), 64 (1966).

    Google Scholar 

  76. M. Graz, M. Gutierrez, T. Palma, J. C. Toha, and C. Winkler,Arch. Biol. Med. Exp.,11(3), 61 - 67 (1978).

    Google Scholar 

  77. Z. We and Ch. Liu,Zhongguo Kexue lishu Daxue Xuebao,16(1), 30 - 37 (1986).

    Google Scholar 

  78. A. Chose, S. K. Canguly, and J. Kaur,Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.,44(2), 175 - 181 (1983).

    Google Scholar 

  79. T. Sato and W. Nakamura,Nippon Igaku Hosbasem Gakkai Zasshi.,41(9), 868 - 872 (1981).

    Google Scholar 

  80. M. N. Srinivasan, R. C. Sarin, and S. K. Basu,Indian J. Exp. Biol.,27(7), 640 - 643 (1989).

    Google Scholar 

  81. N. I. Lisina, M. M. Vigdorchik, L. Kh. Vinograd, and G. N. Il' ina, in:Abstrs. of the 4th All-Union Conf. [in Russian], Moscow (1990), pp. 43–44.

  82. P. G. Zherebchenko, in:The Antiradiation Properties of Indolylalkylamines [in Russian], Atomizdat, Moscow (1971), pp. 69–89.

  83. L. A. Davankova,Dissertation, Izd. MKhTI im. D. I. Mendeleeva, Moscow (1971).

    Google Scholar 

  84. L. A. Davankova, A. D. Neklyudov, L. A. Shchukina, and N. N. Suvorov,Zh. Obshch. Khimii,41(4), 2786 - 2791 (1971).

    Google Scholar 

  85. A. D. Neklyudov, L. A. Shchukina, and N. N. Suvorov,Zh. Obshch. Khimii,37(4), 797 - 800 (1967).

    Google Scholar 

  86. L. A. Shchukina, N. N. Suvorov, and A. D. Neklyudov,Zh. Obshch. Khimii,37(3), 578 - 582 (1967).

    Google Scholar 

  87. L. A. Shchukina, N. N. Suvorov, L. A. Davankova, and A. D. Neklyudov,Zh. Obshch. Khimii,41, 1626 - 1629 (1971).

    Google Scholar 

  88. L. A. Shchukina, N. N. Suvorov, A. D. Neklyudov, and N. P. Sorokina,Izv. Akad. SSSR. Ser. Khim., No. 1, 107 - 111 (1966).

    Google Scholar 

  89. N. S. Suvorov, G. V. Popova, A. D. Neklyudov, E. V. Tsvetkov, K. F. Turgin, A. P. Kiselev, and L. N. Yaskevich,Zh. Obshch. Khimii,52(10), 2337 - 2342 (1982).

    Google Scholar 

  90. N. N. Suvorov, M. D. Mashkovskii, A. D. Neklyudov, M. é. Kaminka, and L. A. Shchukina,Bioorg. Khimiya,2(6), 729 - 736 (1976).

    Google Scholar 

  91. L. M. Il'yuchenok, V. I. Butaeva, and Yu. A. Davidovich,Radiobiologiya,22(2), 269 - 275 (1982).

    Google Scholar 

  92. L. F. Semenov,Experimental Studies of the Prophylaxis of Radiation Sickness [in Russian], Leningrad (1967), p. 93.

  93. I. P. Tregubenko, B. N. Lapin, and I. Ya. Postovskaya,Synthesis and Studies of the Properties and Uses of Detoxified Compounds [in Russian], Sverdlovsk (1971), pp. 33–34.

  94. G. G. Vatulina, T. N. Tuzhilkova, T. V. Matveeva, V. P. Krasnov, N. L. Burde, and L. V. Alekseeva,Khim. Farm. Zh.,20(9), 1078 - 1083 (1986).

    Google Scholar 

  95. G. L. Floersheim, N. Chiodetti, and A. Bieri,Br. J. Radiol.,61(726), 501 - 508 (1988).

    Google Scholar 

  96. M. Pospisil, J. Netikova, A. Kozubik, and K. S. Chertkov,Radiobiol. Radiother.,29(1), 101 - 108 (1988).

    Google Scholar 

  97. O. Shledovsky and K. Chledovska,Radiobiol. Radiother.,31(2), 73 - 78(1987).

    Google Scholar 

  98. O. Shledovsky and K. Chledovska,Radiobiol. Radiother.,28(4), 499 - 505 (1987).

    Google Scholar 

  99. M. Pospisil, J. Netikova, I. Pipolova, and J. Mikeska,Folia Biol.,26(1), 53 - 61 (1980).

    Google Scholar 

  100. Z. M. Bacq,Acta Radiol.,41, 47 - 55 (1954).

    Google Scholar 

  101. K. Fleming,Naturwissenschaften,44, 239 (1957).

    Google Scholar 

  102. Ph. E. Hartman, Z. Hartman, and M. J. Gitardi,Radiat. Res.,114(2), 319 - 330 (1988).

    Google Scholar 

  103. S. E. Severin, A. A. Boldyrev, S. L. Stvolinskii, M. M. Bordyukov, E. N. Goncharenko, I. E. Malinina, Yu. B. Kudryashov, and L. I. Dev,Radiobiologiya,30(6), 745 - 748 (1990).

    Google Scholar 

  104. J. R. Piper, L. M. Rose, A. G. Laseter, and M. M. Grenan,J. Med. Chem.,17, 1119 - 1120 (1974).

    Google Scholar 

  105. S. K. Khalikov and D. Kh. Khamidov,Abstrs. of the 12th All-Union Conf. on the Pharmacol. of Antirad. Preparations [in Russian], Moscow (1972), pp. 31–34.

  106. S. K. Khalikov, Ya. Kh. Turakulov, and M. M. Rakhimov,Radiobiologiya,15(6), 910 - 913 (1975).

    Google Scholar 

  107. E. V. Grishin, A. P. Sukhikh, L. N. Slobodyan, Yu. A. Ovchinnikov, and V. M. Sorokin,FEBS Lett. (Netherl.),45(1), 118 - 121 (1974).

    Google Scholar 

  108. E. V. Grishin, A. P. Sukhikh, T. B. Adamovich, Yu. A. Ovchinnikov, and L. Ya. Yukelson,FEBS Lett.,48(2), 179 - 183 (1974).

    Google Scholar 

  109. Kh. S. Mukhamedzhanov, F. Yu. Mametov, K. S. Khalikov, and Z. S. Khudaikulova,Radiobiologiya,21(6), 918 - 922 (1981).

    Google Scholar 

  110. L. A. Vernigorova and V. G. Lebedev,Radiobiologiya,26(4), 532 - 535 (1986).

    Google Scholar 

  111. A. V. Val'dman, V. I. Ratnikov, N. V. Makarova, and M. M. Kozlovskaya,Byull. éksp. Biol. Med.,95(5), 34 - 35 (1983).

    Google Scholar 

  112. T. Yu. Il'yuchenok, I. K. Vytchanikov, A. Ya. Sinka, L. M. Frigidova, V. P. Lepikhin, and K. S. Shadurskii,Farmakol. Toksikol.,37(3), 367 - 371 (1974).

    Google Scholar 

  113. Y. Lai, Y. Fang, R. Wang, and W. Cao,Yingyang Xuebao,4(2), 145 - 151 (1982).

    Google Scholar 

  114. Yu. A. Davidovich, T. N. Golovina, L. N. Mal'tseva, and T. N. Tuzhilkova, in:Abstrs. of the 4th All-Union Conf. [in Russian], Moscow (1990), pp. 21–22.

  115. A. G. Sverdlov, S. A. Grachev, A. V. Bogatyrev, A. I. Shabarova, G. A. Bagiyan, and S. I. Timoshchenko,Radiobiologiya,

  116. A. G. Sverdlov, A. V. Bogatyrev, N. G. Nikanorova, S. I. Timoshenko, and G. I. Kalmykova,Radiobiologiya,19(2), 293 - 296 (1979).

    Google Scholar 

  117. A. G. Sverdlov, S. A. Grachev, G. N. Bondarev, A. V. Bogatyrev, P. G. Nikanorova, S. I. Timoshenko, G. I. Kalmykova, and G. I. Krasotskaya,Radiobiologiya,20(2), 269 - 272 (1980).

    Google Scholar 

  118. A. G. Sverdlov, A. V. Bogatyrev, A. I. Shabarova, S. I. Timoshenko, P. G. Nikanorova, T. V. Kavuksan, and T. N. Mikhno, in:Abstrs. of the 12th All-Union Conf. on the Pharmacol. of Antirad. Preparations [in Russian], Moscow (1972), p. 62.

  119. M. Fatome,Radioprotection,16(2), 113 - 119 (1981).

    Google Scholar 

  120. J. W. Harris and T. L. Phillips,Rad. Res.,46(3), 362 - 379 (1971).

    Google Scholar 

  121. P. Kuna,Vojen. Zdrav. Lysty,48(2), 58 - 62 (1979).

    Google Scholar 

  122. P. Kuna, P. Petyrek, V. Jensovsky, and J. Melek,Radiobiol. Radiother.,22(5), 644 - 649 (1981).

    Google Scholar 

  123. M. Wagner, H. Sedlmeier, E. Metzger, T. Wustrov, and O. Messerschmidt,Strahlentherapie,156(9), 655 - 662 (1980).

    Google Scholar 

  124. J. M. Yuhas,Radiat. Res.,47, 562 - 565 (1971).

    Google Scholar 

  125. J. R. Piper, C. R. Stringfellow, R. Elliot, and T. P. Johnston,J. Med. Chem.,12(2), 236 - 243 (1969).

    Google Scholar 

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  1. A. L. Mndzhoyan Institute of Fine Organic Chemistry, Armenian Academy of Sciences, Erevan, Armenia

    S. A. Kazaryan, K. P. Grigoryan, S. N. Airapetyan & O. L. Mndzhoyan

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Kazaryan, S.A., Grigoryan, K.P., Airapetyan, S.N. et al. Derivatives of natural amino acids as radioprotectors (review). Pharm Chem J 29, 454–458 (1995). https://doi.org/10.1007/BF02219999

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