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Pharmaceutical Chemistry Journal

, Volume 29, Issue 1, pp 39–41 | Cite as

Synthesis and antitumor activity of substituted thiosemicarbazones of heterocyclic carboxaldehydes and their chelates with transition metal ions

  • T. R. Ovsepyan
  • J. M. Terdzhanyan
  • F. G. Arsenyan
  • G. M. Stepanyan
  • B. T. Garibdzhanyan
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Abstract

We synthesized new copper complexes of 4-methyl-, 4-phenyl-, 4-(4-alkoxybenzyl)-substituted thiosemicarbazones of 2-formylfuran and 2,2-dimethyl-4-formyltetrahydropyran. We discuss the spectral data and compare the antitumor properties of the ligands and complexes. The ligands were found to have a high therapeutic efficacy.

Keywords

Copper Organic Chemistry Spectral Data Antitumor Activity Therapeutic Efficacy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • T. R. Ovsepyan
    • 1
  • J. M. Terdzhanyan
    • 1
  • F. G. Arsenyan
    • 1
  • G. M. Stepanyan
    • 1
  • B. T. Garibdzhanyan
    • 1
  1. 1.Institute of Fine Organic ChemistryArmenia National Academy of Sciences of the Republic of ArmeniaErevanArmenia

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