The ultrastructure of the retina after a single dose of etomidate

  • M. Antal


There were no pathological changes in the layers of the rabbit retina 20 and 48 h following the administration of 2 mg/kg body wt. of etomidate (Hypnomidate, Janssen), given intravenously. On the basis of our experiments, it can be said that although retinal changes might be expected after a larger dose and/or after longer exposure, the dosage usually used in clinical practice for induction of narcosis does not bring about pathological alterations.


Public Health Clinical Practice Retina Single Dose Pathological Change 
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  1. 1.
    Antal M (1981) Etomidate induced retinal changes Albrecht von Graefes Arch Klin Ophthalmol 215:193–201Google Scholar

Copyright information

© Springer-Verlag GmbH & Co. KG 1982

Authors and Affiliations

  • M. Antal
    • 1
  1. 1.Department of Anaesthesia and Intensive CareHospital “Jahn Ferenc”BudapestHungary

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