Abstract
Using a kinetic turbidimetric assay based on the binding of serum glycoprotein to concanavalin A the acute phase reaction has been detected in dogs. Raised levels of glycoprotein were found in dogs which had undergone surgery, had been treated with bacterial endotoxin and had various inflammatory conditions.
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Allen, R.C., Bienvenu, J., Laurent, P. and Suskind, R.M., 1982. Marker proteins in inflammation. de Gruyter, New York.
Bittiger, H. and Schnebli, H.P., 1976. Concanavalin A as a tool. John Wiley & Sons, London.
Caspi, D., Baltz, M.L., Snel, F., Gruys, E., Niv, D., Batt, R., Munn, E.A., Buttress, N. and Pepys, M.B. 1984. Isolation and characterisation of C-reactive protein from the dog. J. Immunol. 53:307–314.
Kohn, J., Whicher, J., Warren, C. and O'Kelly, T. 1980. The use of lectins to measure acute phase proteins in the serum or plasma of man and animals during inflammation and tissue breakdown. FEBS Letters 109:257–260.
Kushner, L., Volanakis, J.E. and Gewurz, H. 1980. C-reactive protein and the plasma protein response to tissue injury. Ann. N.Y. Acad. Sci. 389:1–479.
Spencer, K., Price, C.P., Anthony, F. and Wood, P.J. 1979. Kinetic immunoturbidimetry: the measurement of pregnancy specific B glycoprotein. Clin. Chim. Acta. 99:177–187.
Warren, C., Whicher, J. and Kohn, J. 1980. The use of concavalin A to measureacute phase proteins bylasernephelometry. J. Immunol. Met. 32:142–150.
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Eckersall, P.D., Sullivan, M., Kirkham, D. et al. The acute phase reaction detected in dogs by concanavalin A binding. Vet Res Commun 9, 233–238 (1985). https://doi.org/10.1007/BF02215147
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DOI: https://doi.org/10.1007/BF02215147