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Effect of histamine on blood flow to the adrenal glands of pigs

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Abstract

Blood flow to the adrenal glands was measured with radioactive microspheres labeled with85Sr in 25–37 kg pigs following the intravenous infusion of physiological saline solution or histamine solution (2 ug/kg/min) for 60 minutes. Total blood flow averaged 2.28 ml/min/gland for control pigs and 4.38 ml/min/gland for histamine-treated pigs (P<.0005). Mean blood flow to the adrenal glands of histamine-treated pigs (3.15 ml/min/g) was 82% higher than that of control pigs (1.73 ml/min/g); the difference was highly significant (P<.0005). The result of this study showed that histamine caused an increased blood flow to the porcine adrenal glands.

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Authors and Affiliations

  1. Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, 99164, Pullman, Washington, (U.S.A.)

    C. S. Zamora & V. K. Reddy

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  1. C. S. Zamora
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  2. V. K. Reddy
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Zamora, C.S., Reddy, V.K. Effect of histamine on blood flow to the adrenal glands of pigs. Vet Res Commun 5, 377–382 (1981). https://doi.org/10.1007/BF02215008

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