Skip to main content
Log in

Effect of prostagladin F2 alpha on the bovine fetal ruminal wall in vitro

  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

Strips of rumen wall from bovine fetuses were incubated in an organ bath with prostaglandin F2 alpha (0.13 to 33.76 μg/ml). The highest reactivity with a submaximal dose (17.03 μg/ml) was observed in the period between 3.0 and 7.9 months of fetal age. A smaller response, but higher than in 1.0 to 2.9 months old fetuses, was observed in the 8.0 to 8.9 months fetuses. The period of the highest reactivity to prostaglandin F2 alpha coincides with the age of onset of papillary morphogenesis and the period of highest reactivity to autonomic and putative transmitter drugs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Arias, J.L., 1978. Estudio histológico del plexo mientérico en omasum de ovino y bovino. Arch. Med. Vet. (Chile), 10: 79–81.

    Google Scholar 

  • Arias, J.L. Cabrera, R. and Valencia, A., 1978. Observations on the histological development of the bovine rumen mucosa. Morphological changes due to age. Anat., Histol., Embryol., Zbl. Vet. Med. C, 7: 140–151.

    Google Scholar 

  • Arias, J.L., Zurich, L. and Pedreros, S., 1979a. Cholinergic reactivity of the bovine fetal ruminal wall in vitro. Vet. Sci. Commun., 3: 141–145.

    Google Scholar 

  • Arias, J.L., Fernández, M.S. and Cabrera, R., 1979b. Distribution and nature of desmosomes in the bovine developing ruminal epithelium. Acta Anat., 105: 309–313.

    PubMed  Google Scholar 

  • Arias, J.L., Zurich, L. and Cox, F., 1980a. Efecto de las catecolaminas en la pared del rumen fetal bovino. Arch. Med. Vet. (Chile), 12: 252–257.

    Google Scholar 

  • Arias, J.L., Zurich, L. and Bastias, J., 1980b. Motor responses to 5-HT of the bovine rumen wall in vitro during fetal development. Pharmacol. Res. Commun., 12: 975–985.

    PubMed  Google Scholar 

  • Arias, J.L., Vial, E. and Cabrera, R., 1980c. Observations on the histogenesis of bovine ruminal papillae. Am. J. vet. Res., 41: 174–178.

    PubMed  Google Scholar 

  • Arias, J.L., Fernández, M.S. and Cabrera, R., 1980d. Glycogen in the epithelium of the bovine fetal rumen. Acta Anat., 106: 216–222.

    PubMed  Google Scholar 

  • Bennett, A., Stamford, I. and Stockey, H., 1977. Estimation and characterisation of prostaglandins in the human gastrointestinal tract. Br. J. Pharmacol., 61: 579–586.

    PubMed  Google Scholar 

  • Burnstock, G., 1979a. In: C. McC. Brooks, K. Koizumi and A. Sato (Editors), Integrative Functions of the Autonomic nervous System. University of Tokyo Press, Tokyo, pp. 145–158.

    Google Scholar 

  • Burnstock, G., 1979b. Autonomic innervation and transmission. Br. med. Bull., 35: 255–262.

    PubMed  Google Scholar 

  • Calzada, J., 1964. Métodos estadísticos para la investigación. Ed. Sesator, Lima, Perú.

    Google Scholar 

  • Coceani, F. and Wolfe, L.S., 1966. On the action of prostaglandin E1 and prostaglandins of the brain on the isolated rat stomach. Can. J. Physiol. Pharmacol., 44: 933–950.

    PubMed  Google Scholar 

  • Coceani, F., Pace-Asciak, C., Volta, F. and Wolfe, L.S., 1967. Effect of nerve stimulation on prostaglandin formation and release from the rat stomach. Am. J. Physiol. 213: 1056–1064.

    PubMed  Google Scholar 

  • Eley, F., Tatcher, W., Bazer, F., Wilcox, C., Becker, R., Head, H. and Adkinson, R., 1978. Development of the conceptus in the bovine. J. Dairy Sci., 61: 467–473.

    PubMed  Google Scholar 

  • Ferreira, S.H., Herman, A. and Vane, J., 1976. Prostaglandin production by rabbit isolated jejunum and its relationships to the inherent tone of the preparation. Br. J. Pharmacol., 56: 469–477.

    Google Scholar 

  • Habel, R., 1956. Anatomical innervation of the ruminant stomach. Cornell Vet., 46: 555–633.

    PubMed  Google Scholar 

  • Hart, S.L., 1971. The actions of prostaglandins E2 and F2 alpha on human foetal intestine. Br. J. Pharmacol., 42: 159–160.

    PubMed  Google Scholar 

  • Leat, W.N.F., 1970. Carbohydrate and lipid metabolism in the ruminant during postnatal development. In: A.T. Phillipson (Editor), Physiology of Digestion and Metabolism in the Ruminant. Oriel Press, Newcastle upon Tyne, England, pp. 211–222.

    Google Scholar 

  • Morrison, R. and Habel, R., 1964. A quantitative study of the distribution of vagal nerve endings in the myenteric plexus of the ruminant stomach. J. comp. Neurol., 122: 297–309.

    PubMed  Google Scholar 

  • Roberts, S.J., 1956. Veterinary Obstetrics and Genital Diseases. Ithaca, New York, 1st ed., p. 19.

  • Sanders, K.M., 1978. Endogeneous prostaglandin E and contractile activity of isolated smooth muscle. Am. J. Physiol., 234 (E): 209–212.

    Google Scholar 

  • Sanders, K.M. and Ross, G., 1978. Effects of endogeous prostaglandins E on intestinal mobility. Am. J. Physiol., 234 (E): 204–208.

    Google Scholar 

  • Taneike, T. and Ohga, A., 1975. Intrinsic innervation of isolated smooth muscle of ruminant forestomach. Jap. vet. Sci., 21: 349–353.

    Google Scholar 

  • Wardrop, L.D., 1961. Some preliminary observations on the histological development of the forestomach of the sheep. J. agric. Sci., 57: 335–341.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Arias, J.L., Zurich, L. & Gonzalez, C.M. Effect of prostagladin F2 alpha on the bovine fetal ruminal wall in vitro. Vet Res Commun 5, 151–158 (1981). https://doi.org/10.1007/BF02214979

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02214979

Keywords

Navigation