Veterinary Research Communications

, Volume 10, Issue 1, pp 1–20 | Cite as

Drug-induced thrombocytopenia

  • Prem J. Handagama
  • Bernard F. Feldman


A variety of drugs may cause thrombocytopenia. Although it occurs more often than drug-induced anemia it is less well understood because techniques for studying drug-platelet-immune interactions have been unavailable until recently. The mechanisms by which drugs cause thrombocytopenia are varied. Bone marrow suppression or increased peripheral destruction of platelets could be involved. Nonimmunologic as well as immunologic mechanisms may also occur. These different mechanisms of drug-induced thrombocytopenia are reveiwed. Diagnostic methods and treatment are also summarized.


Public Health Bone Marrow Anemia Thrombocytopenia Veterinary Medicine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Elsevier Science Publishers B.V 1986

Authors and Affiliations

  • Prem J. Handagama
    • 1
  • Bernard F. Feldman
    • 1
  1. 1.Department of Clinical PathologyUniversity of CaliforniaDavisUSA

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