References
American Psychiatric Association. (1980).Diagnostic and statistical manual of mental disorders (3rd ed. pp. 87–90). Washington, DC: Author.
Bregman, J. D., Dykens, E., Watson, M., Ort, S. I., & Leckman, J. F. (1987). Fragile-X syndrome: Variability of phenotypic expression.Journal of the American Academy of Child and Adolescent Psychiatry, 26, 463–471.
Brennand, J., Konecki, D. S., & Caskey, C. T. (1983). Expression of human and Chinese hamster hypoanthine-guanine phosphoribosyltransferase cDNA recombinants in cultured Lesch-Nylan and Chinese hamster fibroblast.Journal of Biological Chemistry, 16, 9593–9596.
Folstein, S. E., & Rutter, M. L. (1987). Autism: Familial aggression and genetic implications. In E. Schopler & G. B. Mesibov (Eds.),Neurobiological issues in autism (pp. 83–105). New York: Plenum Press.
Gitschier, J., Wood, W., Goralka, T., Wion, K., Chen, E., Eaton, D., Vehar, G., Capon, D., & Lawn, R. M. (1984). Characterization of the human factor XIII gene.Nature, 312, 326–330.
Kanner, L. (1943). Autistic disturbances of affective contact.Nervous Child, 2, 217–250.
Oberle, I., Brayna, D., Camerino, G., White, R., & Mandel, G. J. (1985). The telomeric region of the human X chromosome long arm: Presence of a highly polymorphic DNA marker and analysis of recombination frequency.Proceedings of the National Academy of Sciences (USA), 82, 2824–2828.
Patterson, M., Kenwrick, S., Thibodeau, S., Faulk, K., Mattei, M. G., Mattei, J. F., & Davies, K. E. (1987). Mapping of DNA markers close to the fragile site on the human X chromosome at Xq27.3.Nuclear Acid Research, 15, 2639–2651.
Sutherland, G. R. (1979). Heritable fragile sites on human chromosomes. I. Factors affecting expression in lymphocyte cultures.American Journal of Human Genetics, 31, 125–135.
Toniolo, D., D'Urso, M., Martini, G., Persico, M., Tufano, V., Battistuzzi, B., & Luzzato, L. (1984). Specific methylation pattern at the 3′ end of the human housekeeping gene for glucose-6-phosphate dehydrogenase.EMBO Journal, 3, 1987–1997.
Yang, T. P., Patel, P. I., Chinault, A. C., Stout, J. T., Jackson, L. G., Hildebrand, B. M., & Caskey, C. T. (1984). Molecular evidence for new mutation at the “hprt” locus in Lesch-Nyhan patients.Nature, 310, 412–414.
Author information
Authors and Affiliations
Additional information
We acknowledge the following investigators who allowed us to use their probes: Richard Lawn (Factor VIII), Thomas Caskey (HPT), Lucio Luzzatto (G6PD), J. L. Mandel (St-14.1), and Kay Davies (MN12).
Rights and permissions
About this article
Cite this article
Tsai, L.Y., Crowe, R.R., Patil, S.R. et al. Brief report: Search for DNA markers in two autistic males with the fragile X syndrome. J Autism Dev Disord 18, 681–685 (1988). https://doi.org/10.1007/BF02211885
Issue Date:
DOI: https://doi.org/10.1007/BF02211885