Clinical Rheumatology

, Volume 11, Issue 2, pp 231–234 | Cite as

Lack of correlation between anticardiolipin antibodies and peripheral autonomic nerve involvement in systemic lupus erythematosus

  • M. Magarò
  • L. Mirone
  • L. Altomonte
  • A. Zoli
  • S. Angelosante


The presence of anticardiolipin antibodies has recently been related to a clinical complex in which both central and peripheral neurologic damage is included. A series of 27 female patients affected by systemic lupus erythematosus (SLE) was tested for the presence of peripheral autonomic neuropathy and serum anticardiolipin antibody (ACA) levels were determined in each patient by ELISA. Peripheral autonomic impairment was detected in 40.7% of SLE patients and a large number (77.7%) of patients had elevated levels of ACA. No relationship was found between presence of ACA (both for IgG and IgM classes) and the autonomic neuropathy.

Key words

Systemic Lupus Erythematosus Anticardiolipin Antibodies Peripheral Autonomic Neuropathy 


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Copyright information

© Acta Medica Belgica 1992

Authors and Affiliations

  • M. Magarò
    • 1
  • L. Mirone
    • 1
  • L. Altomonte
    • 1
  • A. Zoli
    • 1
  • S. Angelosante
    • 1
  1. 1.Divisione di Reumatologia, Istituto di Clinica MedicaUniversità cattolical del Sacro CuoreRomaItalia

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