Clinical Rheumatology

, Volume 10, Issue 4, pp 426–433 | Cite as

Assessment of inflammatory joint activity in rheumatoid arthritis and changes in atmospheric conditions

  • M. A. F. J. Van De Laar
  • H. J. Bernelot Moens
  • R. J. Van der Stadt
  • J. K. Van der Korst


Seventy-nine patients suffering from rheumatoid factor positive rheumatoid arthritis (RA) were included in this study. In each patient disease activity was assessed three times at two-week intervals during a four-week period. All factors that might possibly influence RA, except atmospheric conditions (AC) were held constant as far as possible. Current AC parameters were obtained from the local observatory of the Royal Dutch Meteorological Institute. There were no relevant correlations between AC and RA variables. Also relations between changes in AC variables preceding the disease activity assessment or between changes in AC variables and RA variables were not seen. By means of factor analysis, uncorrelated factors pertaining to RA or to weather were extracted. No clear association between any of the AC variables and any of the RA variables was noted. Our results do not support the widely accepted, but insufficiently documented, influence of weather on RA.

Key words

Rheumatoid Arthritis Atmospheric Conditions Disease Activity 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Hollander, J.L. The controlled-climate chamber for study of the effects of meteorological changes on human diseases. Trans N Y Acad Sci, 1961, 24, 167–172.PubMedGoogle Scholar
  2. 2.
    Hollander, J.L. The effect of simultaneous variations of humidity and barometric pressure on arthritis. Bull Am Meteorol Soc, 1963, 44, 489–494.Google Scholar
  3. 3.
    Latman, N. Rheumatoid arthritis and climate. N Engl J Med, 1980, 303, 1178.Google Scholar
  4. 4.
    Sibley, J.T. Weather and arthritis symptoms. J Rheumatol, 1985, 12, 707–710.PubMedGoogle Scholar
  5. 5.
    Patberg, W.R., Nienhuis, R.L.F., Veringa, F. Relation between meteorological factors and pain in rheumatoid arthritis in a marine climate. J Rheumatol 1985, 12, 711–715.PubMedGoogle Scholar
  6. 6.
    Dequeker, J., Wuestenraed, L. The effect of biometeorological factors on Ritchie articular index and pain in rheumatoid arthritis. Scand J Rheumatol 1986, 15, 280–284.PubMedGoogle Scholar
  7. 7.
    Rasker, J.J., Peters, H.J.G., Boon, K.L. Influence of weather on stiffness and force in patients with rheumatoid arthritis. Scand J Rheumatol, 1986, 15, 27–36.PubMedGoogle Scholar
  8. 8.
    Guedj, D., Weinberger, A. Effect of weather conditions on rheumatic patients. Ann Rheum Dis, 1990, 49, 158–159.PubMedGoogle Scholar
  9. 9.
    Laar vd, M.A.F.J., Korst vd, J.K. Food intolerance and rheumatoid arthritis I. Ann Rheum Dis (in press).Google Scholar
  10. 10.
    Ropes, M.W., Bennett, G.A., Cobb, S., Jacox, R., Jessar, R.A. 1958 revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis, 1958, 9, 175–176.PubMedGoogle Scholar
  11. 11.
    Steinbrocker, O., Traeger, C.H., Batterman, R.C. Therapeutical criteria in rheumatoid arthritis. JAMA 1949, 140, 659.Google Scholar
  12. 12.
    Ritchie, D.M., Boyle, J.A., McInnes, J.M., Jasani, M.K., Dalakos; Th.G., Grieveson, P., Buchanan, W.W. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis. Q J Med 1968, 37, 393–406.PubMedGoogle Scholar

Copyright information

© Clinical Rheumatology 1991

Authors and Affiliations

  • M. A. F. J. Van De Laar
    • 1
  • H. J. Bernelot Moens
    • 1
  • R. J. Van der Stadt
    • 1
  • J. K. Van der Korst
    • 1
  1. 1.Jan van Breemen InstituutUniversity of AmsterdamAmsterdamThe Netherlands

Personalised recommendations