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The discrimination of various cystine sulfoxides

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Zusammenfassung

L-Cysteinsäure-L-cysteinylester und symmetrischesL-Cystindisulfoxyd wurden als zwei isomere Oxydationsprodukte des Cystins isoliert und durch IR-Spektrum und verschiedenes Verhalten bei der elektrolytischen Reduktion charakterisiert. Mit Hilfe gleichmässiger mechanischer Titration wurden die pH-Beständigkeitsbereiche und das kritische pH beginnender Hydrolyse als abrupte Wendung in der Titrationskurve automatisch registriert.

Die katalytische Wechselwirkung des Cysteins an der rotierenden Platinelektrode wurde indirekt als Endpunktindikation der amperometrischen Titration des Cysteins in Tris-Puffer benutzt.

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Authors and Affiliations

  1. School of Pharmacy, University of California Medical Center, San Francisco, Calif.

    G. E. Utzinger

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  1. G. E. Utzinger
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Additional information

This work was supported by Cancer Research funds of the University of California and also in part by funds of AEC contract No. AT (11-1)-34 Project No. 41. I wish to express my appreciation to DeanT. C. Daniels and Drs.F. Goyan, L. A. Strait, J. C. Craig, E. Jorgensen, andE. Brochmann-Hanssen of the faculty of the School of Pharmacy for support with equipment and counsel.

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Utzinger, G.E. The discrimination of various cystine sulfoxides. Experientia 17, 374–376 (1961). https://doi.org/10.1007/BF02201773

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