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Pathogenesis of the uremic syndrome. Pharmacological studies on acetoin and 2,3-butylene glycol

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Zusammenfassung

Acetoin und 2,3-Butylenglykol entstehen bei Menschen und Tieren aus Brenztraubensäure. Beide Substanzen bewirken bei Mäusen Narkose. Bei Ratten tritt der Bezold-Jarisch-Reflex auf. Die Rolle von Acetoin und 2,3-Butylenglykol bei urämischen und hepatischen Bewusstseinsstörungen wird diskutiert.

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Literatur

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Authors and Affiliations

  1. Medizinische Klinik der Universität Basel, Switzerland

    H. Thölen, F. Bigler & H. Staub

Authors
  1. H. Thölen
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  2. F. Bigler
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  3. H. Staub
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Additional information

The study was aided by grants from ‘Schweizerischer Nationalfonds' and from F. Hoffmann-La Roche & Co. AG, Basel.

3rd Communication. 2nd Commun. see:F. Bigler, H. Thölen, andH. Staub, Helv. physiol. pharmacol. Acta19, C 11 (1961).

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Thölen, H., Bigler, F. & Staub, H. Pathogenesis of the uremic syndrome. Pharmacological studies on acetoin and 2,3-butylene glycol. Experientia 17, 359–360 (1961). https://doi.org/10.1007/BF02201762

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