Advertisement

Neurophysiology

, Volume 20, Issue 1, pp 29–39 | Cite as

Activation of cat pontine nuclei neurons produced by cortico- and cerebellofugal impulses

  • V. V. Fanardzhyan
  • O. P. Kosoyan
  • A. O. Bantikyan
Article

Abstract

Extracellular recording techniques were used on cats anesthetized with Nembutal to illustrate antidromic activation of pontine neurons produced by stimulating the medial and occasionally the superior cerebellar peduncle, the cerebellar central nuclei, pyramidal tract, and sensorimotor region of the cortex. Of the pontine nucleus projection, that extending to the lateral cerebellar nucleus was the most clearly defined. Stimulation of the pyramidal tract, central cerebellar nuclei and the superior cerebellar peduncle was found to produce monosynaptic excitation of pontine neurons. The significance and special features of the connections identified are discussed in connection with cortico-pontocerebellar system function.

Keywords

System Function Pyramidal Tract Central Nucleus Cerebellar Nucleus Nucleus Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    A. S. Amatuni, “Orthodromic activation of neurons belonging to the cat cerebellar vestigial nucleus produced by stimulating the pontine nuclei,” Fiziol. Zh. SSSR,67, No. 2, 191–202 (1981).Google Scholar
  2. 2.
    A. S. Amatuni and V. V. Fanardzhyan, “Electrophysiological analysis of efferent projections from the cat cerebellar vestigial nucleus,” Fiziol. Zh. SSSR,66, No. 8, 1171–1180 (1980).Google Scholar
  3. 3.
    V. N. Kazakov and A. L. Dolgopolov, “Corticofugal influences on the activity of pontine neurons,” Neirofiziologiya,12, No. 4, 358–367 (1980).Google Scholar
  4. 4.
    V. N. Kazakov and A. L. Dolgopolov, “Corticofugal impulses converging on pontine neurons,” Neirofiziologiya,12, No. 5, 274–281 (1980).Google Scholar
  5. 5.
    V. V. Fanardzhyan, A. O. Bantikyan, and O. P. Kosoyan, “Antidromic and synaptic activation of neurons belonging to the reticular formation of Bekhterev's pontine tegmentum produced by cortico- and cerebellofugal impulses,” Fiziol. Zh. SSSR,72, No. 12, 1593–1601 (1986).Google Scholar
  6. 6.
    K. Albus, L. Donate-Oliver, D. Sanides, and W. Fries, “The distribution of pontine projection cells in visual and association cortex of the cat: an experimental study with horseradish peroxidase,” J. Comp. Neurol.,201, No. 2, 175–189 (1981).Google Scholar
  7. 7.
    G. J. Allen, G. B. Azzena, and T. Ohno, “Pontine and nonpontine pathways mediating early mossy fiber responses from sensorimotor cortex to cerebellum in the cat,” Exp. Brain Res.,36, No. 2, 359–374 (1979).Google Scholar
  8. 8.
    G. J. Allen, H. Korn, T. Oshima, and K. Toyama, “The mode of synaptic linkage in the cerebro-ponto-cerebellar pathway of the cat. 2. Responses of single cells in the pontine nuclei,” Exp. Brain Res.,24, No. 1, 15–36 (1975).Google Scholar
  9. 9.
    G. J. Allen, T. Oshima, and K. Toyama, “The mode of synaptic linkage in the cerebroponto-cerebellar pathway investigated with intracellular recording from pontine nuclei cells of the cat,” Exp. Brain Res.,29, No. 1, 123–136 (1977).Google Scholar
  10. 10.
    G. J. Allen and N. Tsukahara, “Cerebrocerebellar communication systems,” Physiol. Rev.,54, No. 4, 957–1006 (1974).Google Scholar
  11. 11.
    J. Altman and A. Bayer, “Prenatal development of the cerebellar system in the rat. II. Cytogenesis and histogenesis of the inferior olive, pontine gray, and precerebellar reticular nuclei,” J. Comp. Neurol.,179, No. 1, 49–76 (1978).Google Scholar
  12. 12.
    P. Angaut, F. Cicirata, and M. R. Ponto, “An autoradiographic study of the cerebellopontine projections from the interposed and lateral cerebellar nuclei in the rat,” J. Hirnfirsch.,26, No. 4, 463–470 (1985).Google Scholar
  13. 13.
    C. Asanuma, W. T. Thach, and E. G. Jones, “Brainstem and spinal projections of the deep cerebellar nuclei in the monkey with observations on the brainstem projections of the dorsal column nuclei,” Brain Res. Rev.,5, No. 3, 229–322 (1983).Google Scholar
  14. 14.
    M. Bentivoglio, G. Macchi, P. Rossini, and E. Tempesta, “Brain stem neurons projecting to neocortex: a HRP study in the cat,” Exp. Brain Res.,31, No. 4, 489–498 (1978).Google Scholar
  15. 15.
    J. R. Bloedel and J. Courville, “Cerebellar afferent system,” in: Motor Control, V. B. Brooks (ed.), American Physiology Society, Bethesda (1981), pp. 735–829.Google Scholar
  16. 16.
    P. Brodal, “The corticopontine projection in the cat. 1. Demonstration of a somatotopically organized projection from the primary sensorimotor cortex,” Exp. Brain Res.,5, No. 3, 210–234 (1968).Google Scholar
  17. 17.
    P. Brodal, “The corticopontine projection in the cat,” Arch. Ital. Biol.,106, No. 4, 310–322 (1968).Google Scholar
  18. 18.
    P. Brodal, “The corticopontine projection in the cat. I. The projection from the proreate gyrus,” J. Comp. Neurol.,142, No. 2, 127–140 (1971).Google Scholar
  19. 19.
    P. Brodal, “The corticopontine projection in the cat. 2. The projection from the orbital gyrus,” J. Comp. Neurol.,142, No. 2, 141–152 (1971).Google Scholar
  20. 20.
    P. Brodal, “The corticopontine projection in the cat. The projection from the auditory cortex,” Arch. Ital. Biol.,110, No. 2, 119–144 (1972).Google Scholar
  21. 21.
    P. Brodal, “The corticopontine projection from the visual cortex in the cat. 1. The total projection and projection from area 17,” Brain Res.,39, No. 2, 297–317 (1972).Google Scholar
  22. 22.
    A. Brodal and P. Brodal, “The organization of the nucleus reticularis tegmenti pontis in the cat, in the light of experimental anatomical studies of its cerebellar cortical afferents,” Exp. Brain Res.,13, No. 1, 90–100 (1971).Google Scholar
  23. 23.
    A. Brodal, J. Destombes, A. M. Lacerda, and P. Angaut, “A cerebellar projection onto the pontine nuclei. An experimental anatomical study in the cat,” Exp. Brain Res.,16, No. 2, 115–139 (1972).Google Scholar
  24. 24.
    A. Brodal and J. Jansen, “The ponto-cerebellar projection in the rabbit and cat,” J. Comp. Neurol.,118, No. 1, 34–118 (1946).Google Scholar
  25. 25.
    V. Chan-Balay, Cerebellar Dentate Nucleus Organization, Cytology and Transmitters, Springer, Berlin (1977).Google Scholar
  26. 26.
    N. M. Gerrits, L. Willemse, V. R. Geest, and M. Kornet, “Some observations on the cerebellopontine projections in the cat with a hypothesis to explain species differences,” Neurosci. Lett.,44, No. 1, 65–70 (1984).Google Scholar
  27. 27.
    B. B. Gould, “Organization of afferents from the brain stem nuclei to the cerebellar cortex in the cat,” Adv. Anat. Embryol. Cell Biol.,62, No. 1, 1–90 (1980).Google Scholar
  28. 28.
    G. H. Hoddevik, “The pontine projection to the flocculonodular lobe and the paraflocculus studied by means of retrograde axonal transport of horseradish peroxidase in the rabbit,” Exp. Brain Res.,30, No. 4, 511–526 (1977).Google Scholar
  29. 29.
    H. Hollander, P. Brodal, and F. Walberg, “Electron-microscopic observations on the structure of the pontine nuclei and the mode of termination of the corticopontine fibers: an experimental study in the cat,” Exp. Brain Res.,7, No. 2, 95–110 (1969).Google Scholar
  30. 30.
    K. Kawamura and T. Hashikawa, “Projections from the pontine nuclei proper and reticular tegmental nucleus onto the cerebellar cortex in the cat. An autoradiographic study,” J. Comp. Neurol.,201, No. 2, 395–413 (1981).Google Scholar
  31. 31.
    R. A. McCrea, G. A. Bishop, and S. T. Kitai, “Electrophysiological and horseradish peroxidase studies of precerebellar afferents to the nucleus interpositus anterior. 2. Mossy fiber system,” Brain Res.,122, No. 2, 215–228 (1977).Google Scholar
  32. 32.
    T. Oshima, “Microphysiology of pontine nuclei in the cat concerning the concept of internal feedback,” in: Cerebro-Cerebellar Interactions, J. Massion and K. Sasaki (eds.), Elsevier, Amsterdam (1979), pp. 125–139.Google Scholar
  33. 33.
    D. Ruegg and M. Wiesendanger, “Corticofugal effects from sensorimotor area I and somatosensory area II on neurons of the pontine nuclei in the cat,” J. Physiol.,247, No. 3, 745–758 (1975).Google Scholar
  34. 34.
    K. Sasaki, S. Kawaguchi, T. Shimoto, and S. Prelevic, “Electrophysiological studies of the pontine nuclei,” Brain Res.,20, No. 3, 425–438 (1970).Google Scholar
  35. 35.
    J. Tomach, “The numerical capacity of the human cortico-pontocerebellar system,” Brain Res.,13, No. 2, 476–484 (1969).Google Scholar
  36. 36.
    M. Wiesendanger, “Cortico-cerebellar loops,” in: Neural Coding of Motor Performance, J. Massion et al. (eds.), Springer, Berlin (1983), pp. 41–53.Google Scholar
  37. 37.
    H. Yuen, R. M. Dom, and G. F. Martin, “Cerebello-pontine projections in the American opossum. A study of their origin distribution and overlap with fibers from the cerebral cortex,” J. Comp. Neurol.,154, No. 3, 257–286 (1974).Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • V. V. Fanardzhyan
  • O. P. Kosoyan
  • A. O. Bantikyan

There are no affiliations available

Personalised recommendations