Psychopharmacologia

, Volume 5, Issue 6, pp 424–430 | Cite as

Avoidance behaviour in the rat after 5-hydroxytryptophan (5-HTP) administration

  • Daphné Joyce
  • H. M. B. Hurwitz
Original Investigations

Keywords

Cage Avoidance Behaviour 

Résumé

L'effet de l'administration du 5-HTP, en doses peu élevées, a été étudié par une méthode utilisant la cage deSkinner: un stimulus auditif annonce l'arrivée d'un choc électrique dans un délai de 9 secondes à moins que l'animal ne presse une barre située dans la paroi de la cage.

Le temps de réaction entre le stimulus conditioné et la réponse conditionée est augmenté après l'administration du 5-HTP et le nombre de chocs reçus par le rat augmente suivant la dose. Les résultats suggèrent que le 5-HTP exerce une action dépressive sous les conditions de cette expérience.

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Copyright information

© Springer-Verlag 1964

Authors and Affiliations

  • Daphné Joyce
    • 1
  • H. M. B. Hurwitz
    • 1
  1. 1.Department of PsychologyBirkbeck CollegeLondon, W.C. 1Great Britain

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